Early-Phase Cancer Trials Clinic

Offering unmatched access to cutting-edge therapies for children and young adults with cancer

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What Sets Us Apart

For children and young adults with relapsed, refractory, or hard‑to‑treat cancers, our Clinic offers a place to explore what comes next—with expanded treatment options, clear guidance, and support at every step.

As one of the nation’s largest programs of its kind, we move discoveries from the laboratory into early‑phase clinical trials, providing access to the most advanced and innovative therapies tailored to each patient’s disease.

Key characteristics that set us apart:

Treating one of the largest populations of children with relapsed or difficult-to-treat tumors, bringing deep expertise in rare and complex cancers
Advanced, personalized care, including immunotherapy and innovative cell and gene therapies, in partnership with the Center for Cell and Gene Therapy and the Precision Oncology Consultation Service
Leadership in national early-phase clinical trial programs that expands access to promising therapies through industry, NCI, and academic partnerships, including the Pediatric Early Phase Clinical Trial Network, CONNECT, Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL), and as an Alex’s Lemonade Stand Developmental Therapeutics Center of Excellence
Close collaboration with your child’s doctor to ensure seamless and coordinated care

Why Texas Children’s Hospital? Pioneering new treatments

With 250+ clinical trials—among the highest of any pediatric cancer center nationwide—we offer access to innovative therapies and expert care.

Clinical trials are integral to pediatric cancer care, and every eligible patient is evaluated for enrollment.

View our featured trials and novel therapies

Approaches

Our Clinic focuses on translating the latest scientific discoveries into innovative therapies for children and young adults. We use state-of-the-art strategies to understand each person’s unique disease and guide families toward the most promising next steps. Learn more about our Approaches.

Mission

At the Early-Phase Cancer Trials Clinic, we are dedicated to:

Precision‑Driven, Personalized Care

Expert care through precision medicine, biomarker profiling, and multidisciplinary collaboration—providing individualized care from diagnosis through transition to adult care

Innovation and Research

Advancing biomarker discovery, cellular and immune‑based therapies and early‑phase drug development to drive progress and shape the future of advanced care

Education and Empowerment

Training future leaders in early‑phase drug development to biomarker‑guided therapeutics while empowering patients with access to cutting‑edge early‑phase clinical trials