Updates

Leading fetal care

Since 2001, Texas Children’s Hospital’s Fetal Center has been at the forefront of innovations in fetal diagnostics and intervention therapies. The following data represents our most recent evaluations, procedures, and outcomes.

Overall fetal center totals

Evaluations
1058 – 2025
13269 – Total

Fetoscopic procedures
154 – 2025
1874 – Total

EXIT (ex-utero intrapartum treatment) procedures
1 – 2025
68 – Total

Open fetal surgeries excluding EXITs
0 – 2025
54 – Total

Fetal echocardiograms
2796 – 2025
37018 – Total

The following data represents evaluations, procedures and outcomes from the Fetal Center's inception through the end of 2025.

Patients evaluated for amniotic band syndrome

  • 0 - 2025
  • 45 - Total

Fetoscopic interventions for amniotic band release

  • 0 - 2025
  • 7 - Total

Survival rate after fetoscopic procedure

  • 100%

Learn more about Amniotic Band Syndrome

Learn more about amniotic band resection

The following data represents evaluations, procedures and outcomes from the Fetal Center's inception through December 2025.

Patients evaluated for CDH

  • 22 – 2025
  • 521 – Total

Number of FETO (fetal endoscopic tracheal occlusion procedures)

  • 3 – 2025
  • 52 – Total

Average number of newborns with CDH cared for each year in NICU

  • 22

Survival to discharge for isolated CDH*

  • 84%

Survival to discharge for CDH with associated anomalies

  • 62%

Learn More about Congenital Diaphragmatic Hernia (CDH)

Learn more about FETO (fetal endoscopic tracheal occlusion procedures)

The following data represents evaluations, procedures and outcomes from the Fetal Center's inception through the end of 2025.

EXIT-to-airway

  • 1 – 2025
  • 45 – Total

EXIT-to-ECMO (extracorporeal membrane oxygenation)

  • 0 – 2025
  • 2 – Total

EXIT-to-resection of high-risk lung mass

  • 0 – 2025
  • 21 - Total

Learn more about EXIT Procedures

Learn more about lung lesions or CCAM

Number of open and catheter-based fetal cardiac interventions

  • 5 – 2025
  • 53 – Total

Number of fetuses undergoing chronic maternal hyperoxygenation for borderline left heart

  • 0 – 2025
  • 14 – Total

Learn more about Fetal Cardiac Intervention

Learn more about hypoplastic left heart syndrome

The following data represents evaluations, procedures and outcomes from the Fetal Center's inception through the end of 2024.

All Patients evaluated for Congenital Lung Malformation (CLM)

  • 20 – 2024
  • 429 – Total

Patients evaluated for high risk CLM*

  • 0 – 2024
  • 91 – Total

Survival to discharge for low risk CLM**

  • 99%

Survival to discharge for high risk CLM

  • 85%

Open fetal surgeries for CLM

  • 0 – 2024
  • 4 – Total

Survival to discharge for open fetal surgeries for CLM

  • 75%

EXIT to resection for CLM

  • 0 – 2024
  • 21 – Total

Survival to discharge for EXIT to resection procedures

  • 95%

*Defined as those with hydrops or CLM volume ratios ≥ 1.6
**Two deaths due to non-pulmonary-related problems

Learn more about open fetal surgeries for CCAM

Learn more about EXIT-to-resection procedures

The following data represents evaluations, procedures and outcomes from the Fetal Center's inception through the end of 2024.

Patients evaluated for fetal tumors, including cervical, mediastinal and sacrococcygeal teratomas

  • 0 – 2024
  • 82 – Total

Patients evaluated for fetal neck masses (lymphatic malformations)

  • 0 – 2024
  • 68 – Total

EXIT-to-airway procedures performed to treat patients with cervical tumors or epignathic tumors, and lymphatic malformations

  • 0 – 2024
  • 30 – Total

Learn more about Fetal Tumors

Learn more about Neck Masses

Learn more about EXIT-to-airway procedures

The following data represents procedures and outcomes from the Fetal Center's inception through December 2024.

Our center has one of the largest number of patients enrolled in a clinical trial for FETO balloon placement in left, right and bilateral CDH with some of the best outcomes in the US.

Fetal endotracheal occlusion cases lsolated (n=39)* Non-Isolated (n=11)
Gestational age at delivery
Median [range]
Mean
35.95 (30.7 - 40.1]
35.8 ± 2.1
36.1 [32.9 - 38.7]
35.9 ± 1.6
ECMO 13/38 (34%) 6/9 (67%)**
Survival to discharge 28/38 (74%) 5/11 (45%)
Length of stay in NICU (days)
Median (range)
Mean
81 (30 - 293)
109 ± 70.4
146 (56 - 235)
146 ± 57
Discharged home on oxygen 13/28(46%) 5/ 5 (100%)

Data are expressed as median [minimum maximum range], mean ± standard deviation, or as numerator/denominator (percentage).
* 1 IUFD at 33.7 weeks gestation
** 4 neonatal deaths <24 hours of life

The following data represents evaluations, procedures and outcomes from the Fetal Center's inception through the end of 2025.

Evaluations for gastroschisis

  • 15 – 2025
  • 34 – Total

Gastroschisis procedures

  • 3 – 2025
  • 4 – Total

Learn more about Gastroschisis

The following data represents evaluations, procedures and outcomes from the Fetal Center's inception through the end of 2025.

Patients evaluated for LUTO

  • 21 – 2025
  • 259 – Total

Fetal bladder shunts

  • 7 – 2025
  • 105 – Total

Learn more about Lower Urinary Tract Obstruction (LUTO)

Learn more about fetal bladder shunts

The following data represents evaluations, procedures and outcomes from December 2011 through the end of December 2025.

Patients evaluated for NTD

49 – 2025

766 – Total

Fetal NTD Repair

  • Open fetal procedures
    • 0 – 2025
    • 45 – Total
  • Fetoscopic procedures
    • 24 – 2025
    • 215 – Total

Fetal NTD repair outcomes

Fetal myelomeningocele
(MMC) repair cases
All fetoscopic
coses (n=215)
MOMS trial
(n=78)
Geshltional ege at delivery
Median (range)
Mean
37 [25.1- 40.9]
36 ± 3.4
34.1 ± 3.1
Preterm premature rupture of membraoos
<37 weeks gestation
74/ 211 (35%)35/78 (45%)
Preterm Delivery
<37 weeks gostetion
<30 weeks gestation
99/204 (49%)
12/ 204 (6%)
62/78(79%)
10/78 (13%)
Vaginal delivery96/204 (47%)0/78 (0%)
Treatment for hydrocephalus
at 12 months or less
67/175 (37%) **31/78 (40%)

*Excludes 5 IUFDs 
**Only includes patients who have reached 12 months of oge

Walking Status at 30 months for fetoscopic repair

Below you will find a detailed report for walking status for our fetoscopic cases. We believe that the details regarding walking status as reported here are important to provide to families. Not every center defines walking independently in the same manner. Here at Texas Children's Fetal Center we take a conservative approach when classifying walking status. We have looked at every child who has had a fetoscopic repair to determine their primary method of daily ambulation at 30 months or above.  Many children are able to take a few steps independently, but when we classify a child as walking independently, that reflects their primary method of ambulation in their daily life. 85% of our fetoscopic patients are able to walk, whether it be independently, with orthotics and/or devices like a walker.

TCH Fetoscopic results - 30 Months and older MOMs trial results - 30 Months and older 
Walking Status Count Percentage Walking Status Count Percentage 
Walking – any form 6087% Walking – any form 4471% 
Walking – independent of braces or walker 17 25% Walking – independent of braces or walker2642%
Walking  – with orthotics 2425% Walking – with orthotics or devices1829%
Walking – with devices 1928% 
None – wheelchair dependent 9 13% None – wheelchair dependent1829%
Total # of patients with available information 69 Total # of patients with available information 62 

*Adzick, S., Thom, E., Spong, C., Brock, J., Burrows, P., Johnson, M.,… Farmer, D. (2011). A randomized trial of prenatal versus postnatal repair of myelomeningocele. New England Journal of Medicine, 364, 993-1004.

Belfort, M., Whitehead, W., Shamshirsaz, A., Bateni, Z., Olutoye, O. O., Olutoye, O.A., …Cass, D. (2017). Fetoscopic open neural tube defect repair: Development and refinement of a two-port, carbon dioxide insufflation technique. Obstetrics and Gynecology, 4, 734-743.

Learn more about Neural Tube Defects (NTD) - Spina Bifida

Learn more about fetoscopic procedures

The following data represents evaluations, procedures and outcomes from the Fetal Center's inception through the end of 2024.

Patients evaluated for omphalocele

  • 8 – 2024
  • 165 – Total

Survival for isolated omphalocele in live-born infants

  • 94%

Learn more about Omphalocele

The following data represents evaluations, procedures and outcomes from the Fetal Center's inception through the end of 2025.

Open procedures

  • 0 – 2025
  • 54 – Total

Cardiac teratoma

  • 0 – 2024
  • 1 – Total

Lung lesions and teratomas

  • 0 – 2024
  • 8 – Total

Neural tube defects

  • 0 – 2024
  • 45 – Total

Learn more about Open Fetal Surgery for SCT & Vascular Tumors

Learn more about Open Fetal Surgery for Lung Masses/CCAM

Learn more about Open Fetal Surgery for Spina Bifida

 Overall TTTS survival

  • 90.1% survival of at least one twin
  • 67.9% survival of both twins

Survival per Quintero stage

StageTwo SurvivorsOne SurvivorNo Survivors
I63 (82.9%)11 (14.5%)2 (2.6%)
II107 (75.4%)21 (14.8%)13 (9.2%)
III145 (59.4%)69 (28.3%)29 (11.9%)
IV15 (57.7%)7 (26.9%)4 (15.4%)

Survival by gestational age at procedure

Gestational ageTwo SurvivorsOne SurvivorNo Survivors
16‐18 weeks107 (59.4%)46 (25.6%)25 (13.9%)
19‐21 weeks132 (72.5%)32 (17.6%)18 (9.9%)
22‐24 weeks65 (67.7%)26 (27.1%)5 (5.2%)
25‐27 weeks26 (86.7%)4 (13.3%)0 (0%)

Learn more about Twin-Twin Transfusion Syndrome (TTTS)

*This data excludes Triplets, TAPS, etc. Only includes true TTTS mo/di twins with and without sFGR

57 cases excluded: no 30 day outcomes available to us


 

Fetal Cardiology Program

Learn more about volumes and outcomes for those patients treated by the Fetal Cardiology program.