Texas Children's Feigin Center is a hub for pediatric research. The facility provides researchers space to intensify their research in areas of fundamental importance in microbiology, immunology, cell biology and sciences of infection and inflammation. Researchers at the Feigin Center are making landmark discoveries and fundamental contributions to the fields of pediatric cancer, women's health and blood disorders. They are also learning how to genetically manipulate tumor cells to make effective cancer vaccines and how to enhance patients' own immune cells to enable them to attack cancers directly.
The Jan and Dan Duncan Neurological Research Institute (NRI)
The Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital (NRI) is the basic research institute dedicated to improving the lives of patients facing devastating neurological disorders. NRI is committed to understanding the pathogenesis of neurological diseases with the ultimate goal of developing treatments.
Collaboration and leadership in genetics and neuroscience have allowed faculty at Baylor College of Medicine and Texas Children's Hospital to discover the underlying causes of dozens of neurological disorders. It is the world’s first basic research institute dedicated to childhood neurological diseases, with the goal of accelerating the pace of discoveries related to brain development and function. In its first five years, the NRI has demonstrated its ability to fulfill that mission with accomplishments that include significant research breakthroughs, grants and faculty awards.
Dr. Huda Y. Zoghbi, director of the NRI, professor of neurology, neuroscience, pediatrics, and molecular and human genetics at Baylor College of Medicine (BCM), and Howard Hughes Medical Institute investigator, credits the institute’s progress to its multi-disciplinary research team, its collaborative approach and a strong infrastructure of core facilities. Dr. John Swann, the co-director of NRI, also heads the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories dedicated to basic research in childhood epilepsies.
The NRI has about 30 principal investigators and over 150 researchers who study varied disciplines such as genetics, neurobiology, physics, mathematics, bioinformatics and behavioral psychology. NRI investigators work across a spectrum of diseases including autism, epilepsy, Rett syndrome, cerebral palsy, ataxias, intellectual disabilities and Batten disease. Such studies also impact many adult disorders that share similar symptoms.
The goal of the NRI is to hasten the progress of new clinical studies and trials. Several clinical studies are under way at Texas Children's Hospital and other institutions for treatment of diseases such as epilepsy and Rett syndrome based on discoveries from NRI researchers.
Children’s Nutrition Research Center
The Children's Nutrition Research Center (CNRC) is a unique cooperative venture between Texas Children's Hospital, Baylor College of Medicine and the U.S. Department of Agriculture/Agricultural Research Service. As the first federal nutrition research center to investigate the nutritional needs of pregnant and nursing women, and children from conception through adolescence, the Children's Nutrition Research Center conducts research that helps improve the maternal, infant and child nutrition guidelines used by physicians, parents and others responsible for the care and feeding of children.
The Clinical Research Center
The Clinical Research Center (CRC) provides a clinical research infrastructure for investigators who want to conduct patient-oriented clinical research at Texas Children’s Hospital. The CRC conducts innovative research studies that cut across all disciplines. Many of the studies evaluate the effects of new therapies in children and are intensive in terms of obtaining blood and other biologic samples to learn as much as possible about these therapies.