Huda Y. Zoghbi, MD
- Neurology
Director, Duncan Neurological Research Institute
Ralph D. Feigin, M.D., Endowed Chair
Distinguished Service Professor, Baylor College of Medicine
Investigator, Howard Hughes Medical Institute
Member, American Academy of Arts and Sciences, National Academy of Medicine and National Academy of Sciences
Languages: Arabic, English, French
Departments:
Get to know Huda Y. Zoghbi, MD
Personal Statement
Dr. Huda Y. Zoghbi is the Ralph D. Feigin Professor in the Departments of Pediatrics, Molecular and Human Genetics, Neurology, and Neuroscience, Baylor College of Medicine, and an Investigator for the Howard Hughes Medical Institute. Additionally, Dr. Zoghbi is the director of the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children's Hospital and Baylor College of Medicine (BCM), and was awarded the 2011 Neuroscience Prize of The Peter and Patricia Gruber Foundation for her pioneering work in unlocking the genetic and molecular mysteries behind a number of devastating neurological disorders, including Rett syndrome, spinocerebellar ataxia type 1, and brain tumors called medulloblastomas. Currently Dr. Zoghbi has four major research projects underway in the Zoghbi. For more information on those projects and the Zoghbi lab, go to the NRI website.
Education
| School | Education | Degree | Year |
|---|---|---|---|
| Baylor College of Medicine | Fellowship | Research Fellowship | 1988 |
| Baylor College of Medicine | Residency | Neurology | 1985 |
| Baylor College of Medicine | Residency | Pediatrics | 1982 |
| Baylor College of Medicine | Internship | Pediatrics | 1980 |
| Meharry Medical College School of Medicine | Medical School | Doctor of Medicine | 1979 |
Organizations
| Organization Name | Role |
|---|---|
| Alpha Omega Alpha Medical Honor Society | Member |
| American Academy of Neurology | Member |
| American Neurological Association | Member |
| American Society Human Genetics | Member |
| Child Neurology Society | Member |
Honors and awards
- 2023
-
August M. Watanabe Prize in Translational Research
Indiana University School of Medicine - 2022
-
Elaine Redding Brinster Prize in Science or Medicine
Penn Institute for Regenerative Medicine at the University of Pennsylvania - 2022
-
Kavli Prize in Neuroscience
The Norwegian Academy of Science and Letters - 2020
-
Brain Prize
The Lundbeck Foundation - 2019
-
Victor McKusick Leadership Award
American Society of Human Genetics - 2019
-
National Academy of Inventors
- 2019
-
Norman J. Siegel Award
American Pediatric Society - 2018
-
National Order of the Cedar, Lebanon
Lebanon - 2018
-
Member of American Association of Arts and Sciences
- 2017
-
Canada Gairdner International Award
- 2017
-
Breakthrough Prize in Life Sciences
- 2016
-
Shaw Prize in Life Science and Medicine
- 2016
-
Jesse Stevenson Kovalenko Medal
- 2015
-
Vanderbilt Prize in Biomedical Science
- 2014
-
Sckolnick Prize
McGovern Institute for Brain Research at MIT - 2014
-
March of Dimes Prize in Developmental Biology
March of Dimes - 2014
-
Honorary Doctorate of Science
Yale University - 2013
-
Dickson Prize in Medicine
University of Pittsburg School of Medicine - 2013
-
The Pearl Meister Greengard Prize
The Rockefeller University - 2011
-
Gruber Prize in Neuroscience
- 2009
-
Vilcek Prize for Biomedical Research
- 2009
-
International Rett Syndrome Foundation's Circle of Angels Research Award
- 2009
-
Marion Spencer Fay Award
Drexel University College of Medicine Philadelphia, PA - 2008
-
Texas Women's Hall of Fame Award
Texas Governor's Commission for Women Abilene, TX - 2008
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Honorary Doctorate of Science
Meharry Medical School Nashville, TN - 2007
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Honorary Doctorate of Science
Middlebury College Middlebury, VT - 2007
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Robert J. and Claire Pasarow Foundation Award in Neuropsychiatry
Los Angeles, CA - 2006
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Bristol-Myers Squibb Neuroscience Distinguished Achievement Award
- 2004
-
Elected
National Academy of Sciences - 2004
-
Marta Philipson Award in Pediatrics
Philipson Foundation for Research Stockholm, Sweden - 2004
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Neuronal Plasticity Prize
IPSEN Foundation Lisbon, Portugal - 2001
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Bernard Sachs Award
Child Neurology Society - 2000
-
Elected
Institute of Medicine, National Academy of Sciences - 1998
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Javits Award
NINDS Council, National Institutes of Health - 1998
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Soriano Award
The American Neurological Association - 1998
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Sidney Carter Award
American Academy of Neurology - 1996
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E. Mead Johnson Award
Society of Pediatric Research - 1995
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Kilby Award for Extraordinary Contributions to Society
* Texas Children’s Hospital physicians’ licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician’s office and were not verified by Texas Children’s Hospital.
Highlights
Deep brain stimulation can correct neural malfunction in Rett and MeCP2 duplication syndrome mice
Coffin SL, Durham MA, Nitschke L, Xhako E, Brown AM, Revelli J-P, Gonzalez EV, Lin T, Handler HP, Dai Y, Trostle AJ, Wan Y-W, Liu Z, Sillitoe RV, Orr HT, and Zoghbi HY. 2023. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron, in press.
Kim J, de Haro M, Al-Ramahi I, Garaicoechea L, Jeong H-H, Sonn J, Liu Z, Botas J, and Zoghbi HY. 2023. Evolutionarily conserved regulators of tau identify targets for new therapies. Neuron, in press
He L, Caudill MS, Jing J, Wang W, Sun Y, Tang J, Jiang X, Zoghbi HY. 2022. A weakened recurrent circuit in the hippocampus of Rett syndrome mice disrupts long-term memory representations. Neuron, May18;110(10):1689-1699. E6. PMID: 35290792.
This paper was the subject of a Neuron Editorial by Poll S and Fuhrmann M, May 18;110(10):1606-1608.
Achilly N, Wang W, Zoghbi HY. 2021. Presymptomatic training mitigates functional deficits in Rett syndrome mice. Nature.Apr;592(7855):596-600. PMCID: PMC8093094.
Shao, Y, Sztainberg Y, Wang Q, Bajikar SS, Trostle AJ, Wan Y-W, Jafar-Nejad P, Rigo F, Liu Z, Tang J, Zoghbi HY. 2021. Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome. Sci Transl Med. Mar 3;13(583):eaaz7785. PMID: 33658357.
View a complete list of publications by Huda Y. Zoghbi, M.D.