A collaborative study by Dr. Yang He and team finds new candidates for obesity, postpartum and Alzheimer's disease

Dr. Yang He and team in collaboration with researchers at Baylor College of Medicine, University of Cambridge in UK and other institutions have identified two gene candidates responsible for obesity and postpartum depression as well as Alzheimer's disease.

The first study published in Cell has found TRPC5 as a diagnostic marker of obesity and postpartum depression as well as potential therapeutic strategies to treat these conditions. Studies in cells, animal models and humans showed that TRPC5 acts on distinct neuronal populations in the hypothalamus, a brain region that regulates multiple innate behaviors including feeding, anxiety, socialization and maternal care. Learn More

The second study published in Science Advances, provided new insights into the factors involved in healthy memory and found the conditions associated with memory loss, like Alzheimer’s disease, opening novel avenues for treatment. Learn More