Marissa Spino, DO
- Pathology
Assistant Professor, Department of Pathology, Baylor College of Medicine
Email: mxspinok@texaschildrens.org
Languages: English
Departments:
Get to know Marissa Spino, DO
Dr. Spino is a pathologist with specialization in neuropathology.
Personal Statement
My experience covers a broad array of adult and pediatric neuropathology and surgical pathology cases, as well as the integration of molecular analyses, autopsy, medical trainee education, clinical validations including validation of methylation array, and clinical research. I am dedicated to personalized medicine and the integration of histologic and molecular diagnostics.
Clinical Interests
Central nervous system tumors and epilepsy
Education
| School | Education | Degree | Year |
|---|---|---|---|
| University of Tennessee - Knoxville | Fellowship | Surgical Pathology | 2023 |
| NYU Grossman School of Medicine | Fellowship | Neuropathology | 2020 |
| New York University School of Medicine | Residency | Anatomic Pathology | 2018 |
| Philadelphia College of Osteopathic Medicine | Medical School | Doctor of Medicine | 2015 |
| Kennesaw State University | Bachelors | Bachelor of Science in Biology | 2010 |
| Kennesaw State University | Bachelors | Bachelor of Science in Psychology | 2009 |
Board Certification
American Board of Pathology, Board Certification in Anatomic Pathology and Neuropathology
* Texas Children’s Hospital physicians’ licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician’s office and were not verified by Texas Children’s Hospital.
Research interests
Epigenetics, clinical trials, and molecular neuro-oncology
Galbraith K, Vasudevaraja V, Serrano J, Shen G, Tran I, Abdallat N, Wen M, Patel S, Movahed-Ezazi M, Faustin A, Spino-Keeton M, Roberts LG, Maloku E, Drexler SA, Liechty BL, Pisapia D, Krasnozhen-Ratush O, Rosenblum M, Shroff S, Boué DR, Davidson C, Mao Q, Suchi M, North P, Hopp A, Segura A, Jarzembowski JA, Parsons L, Johnson MD, Mobley B, Samore W, McGuone D, Gopal PP, Canoll PD, Horbinski C, Fullmer JM, Farooqui MS, Gokden M, Wadhwani NR, Richardson TE, Umphlett M, Tsankova NM, DeWitt JC, Sen C, Placantonakis DG, Pacione D, Wisoff JH, Teresa Hidalgo E, Harter D, William CM, Cordova C, Kurz SC, Barbaro M, Orringer DA, Karajannis MA, Sulman EP, Gardner SL, Zagzag D, Tsirigos A, Allen JC, Golfinos JG, Snuderl M. Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors-A prospective study and guidelines for clinical testing. Neuro-Oncology Advances, 2023 Jun 26;5(1):vdad076. doi: 10.1093/noajnl/vdad076. Erratum in: Neuro-Oncology Advances, 2023 Sep 23; 5(1): vdad114. doi: 10.1093/noajnl/vdad114. PMID: 37476329; PMCID: PMC10355794
Tang K, Kurland D, Vasudevaraja V, Serrano J, Delorenzo M, Radmanesh A, Thomas C, Spino M, Gardner S, Allen JC, Nicolaides T, Osorio DS, Finlay JL, Boué DR, Snuderl M. Exploring DNA Methylation for Prognosis and Analyzing the Tumor Microenvironment in Pleomorphic Xanthoastrocytoma. Journal of Neuropathology and Experimental Neurology, 2020 Aug 1; 79(8): 880-890. doi: 10.1093/jnen/nlaa051. PMID: 32594172
Spino M, Snuderl M. Genomic Molecular Classification of CNS Malignancies. Advances in Anatomic Pathology, 2020 Jan;2 7(1): 44-50. doi: 10.1097/PAP.0000000000000254. PubMed PMID:31714292
Mureb M, Benjamin C, Sen C, Spino M, Krasnozhen-Ratush O, Zagzag D, Pavlick AC, Kondziolka D. Gamma Knife Radiosurgery and Immunotherapy as Primary Treatment for a Malignant Tumor of the Cranial Base Beginning as Lentigo Maligna: A Case Report. Practical Radiation Oncology, 2019 Nov;9(6):e608-e612. doi: 10.1016/j.prro.2019.05.010. Epub 2019 May 23. PubMed PMID:31129314
Spino M, Kurz SC, Chiriboga L, Serrano J, Zeck B, Sen N, Patel S, Shen G, Vasudevaraja V, Tsirigos A, Suryadevara CM, Frenster JD, Tateishi K, Wakimoto H, Jain R, Riina HA, Nicolaides TP, Sulman EP, Cahill DP, Golfinos JG, Isse K, Saunders LR, Zagzag D, Placantonakis DG, Snuderl M, Chi AS. Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase-mutant Glioma. Clinical Cancer Research, 2018 Nov 5. doi: 10.1158/1078-0432.CCR-18-2312. PubMed PMID: 30397180