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Texas Medical Center

Phone: 832-824-3278
Fax: 832-826-4287


6651 Main Street
Legacy Tower, 21st Floor
Houston, TX 77030

Christina Y. Miyake, MD, MS

Associate Professor

Baylor College of Medicine


School Education Degree Year
Boston Children's Hospital fellowship Pediatric Cardiology 2009
Boston Children's Hospital residency Pediatrics 2005
Georgetown University medical school Doctor of Medicine 2002
Georgetown University other Masters 1998


Dr. Miyake is a member of the Arrhythmia and Pacing (Electrophysiology) Service and the Cardiovascular Genetics Clinic at Texas Children's Hospital. She specializes in the care of pediatric and adult congenital patients with cardiac arrhythmia disorders. Dr. Miyake is also an adjunct Assistant Professor in the Department of Molecular Physiology and Biophysics at Baylor College of Medicine and is actively involved in basic and translational research. Her goal is to identify the genetic and molecular causes of arrhythmia disorders in order to improve the quality of care and outcomes among patients with arrhythmia disorders.

Her clinical practice largely involves pediatric patients with supraventricular tachycardia, Wolff-Parkinson-White Syndrome and AV block. In addition to cardiac ablation procedures, she also performs cardiac pacemaker and device implantations.

Dr. Miyake has a special interest in arrhythmia disorders that can cause sudden death. She evaluates children and family members with inherited arrhythmia disorders. She is actively involved in the clinical care and research behind Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia, Brugada Syndrome, Arrhythmogenic Cardiomyopathy, and left ventricular noncompaction.

In addition, Dr. Miyake began her career with the first prospective study to minimize radiation exposure during cardiac SVT ablations. She has a strong interest in reducing radiation exposure among children during ablation and device procedures and is a member of the national guidelines committee for ablation of SVT in pediatric patients.

Dr. Miyake is dedicated to her patients and the care she provides. She continually strives to advance the field to improve the quality of care and outcomes for all patients with arrhythmia disorders.

News Articles:

Groundbreaking genetic mutation study underway in Texas Medical Center 


Organization Name Role
American Academy of Pediatrics Member
American College of Cardiology Member
American Heart Association Member
Heart Rhythm Society Member

Selected Publications

Miyake CY, Gauvreau K, Sundel RP, Newburger JW. Characteristics of children discharged from hospitals in the United States in 2000 with the diagnosis of acute rheumatic fever. Pediatrics 2007; 120: 503-508.

Miyake CY, Cecchin F, Walsh EP, Berul CI. Ectopic atrial rhythm is a preablation predictor of atrioventricular nodal reentrant tachycardia in children. Pediatr Cardiol 2008; 29(6):1066-70.

Miyake CY, Mah D, Atallah J, Oikle H, Melgar M, Alexander ME, Berul CI, Cecchin F, Walsh EP, Triedman JK. Nonfluoroscopic Imaging Systems Reduce Radiation Exposure in Children undergoing Ablation of Supraventricular Tachycardia. Heart Rhythm 2011; 8(4): 519-25.

Miyake CY, del Nido PJ, Alexander ME, Cecchin F, Berul CI, Triedman JK, Geva T, Walsh EP. Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia. J Am Coll Cardiol 2011; 58(18) 1903-9.

Miyake CY, Webster G, Czosek RJ, Kantoch MJ, Dubin AM, Avasarala K, Atallah J. Efficacy of implantable cardioverter defibrillators in young patients with catecholaminergic polymorphic ventricular tachycardia: success depends on substrate. Circ Arrhythm Electrophysiol 2013; 6(3): 579-87.

Miyake CY, Davis A, Motonaga KS, Dubin AM, Berul CI, Cecchin F. Neonatal ventricular fibrillation following ST segment changes and QRS widening: a new disease? Circ Arrhythm Electrophysiol 2013; 6 (4):712-8.

Miyake CY, Teele S, Chen L, Motonaga KS, Dubin AM, Blasubramanian S, Rosenthal DN, Alexander ME, Walsh EP, Mah DY. In-hospital arrhythmia development and outcomes in pediatric patients with myocarditis. Am J Cardiol 2014; 113(3):535-40.

Miyake CY, Motonaga KS, Fischer-Colbrie ME, Chen L, Hanisch DG, Balise RR, Kim JJ, Dubin AM. Exertional Syncope in the Pediatric Patient. Accepted for publication. Cardiology in the Young, June 2015.

Chiang DY, Kim JJ, Valdes SO, delaUz C, Fan Y, Orcutt J, Domino M, Smith M, Wehrens XHT, Miyake CY. Loss-of-Function SCN5A Mutations Associated with Sinus Node Dysfunction, Atrial Arrhythmias and Poor Pacemaker Capture. Circ Arrhythm Electrophysiol, June 2015.

Chiang DY, Allen HD, Kim JJ, Valdes SO, Wang Y, Pignatelli RH, Lotze TE, Miyake CY. Relation of cardiac dysfunction to rhythm abnormalities among patients with Duchenne and Becker Muscular Dystrophies. Accepted Am J Card 2016.

Mah D, Miyake C, Clegg R, Mayer J, Walsh EP. Epicardial Left Atrial Appendage to Left Ventricle Accessory Connections. Heart Rhythm 2010. 7(12): 1740-5

Mainwaring RD, Reddy VM, Reinhartz O, Petrossian E, MacDonald M, Nasirov T, Miyake CY, Hanley FL. Anomalous Aortic Origin of a Coronary Artery: Medium-Term Results Following Surgical Repair in 50 Patients. Ann Thorac Surg 2011. 92(2): 691-7.

Hill AC, Miyake CY, Grady SR, Dubin AM. Accuracy of Interpretation of Preparticipation Screening Electrocardiograms. J Pediatr 2011. 159 (5):783-8.

Gupta P, Jines P, Gossett J, Maurille M, Hanley F, Reddy VM, Miyake CY, Roth SJ. Predictors for use of Temporary Epicardial Pacing Wires after Pediatric Cardiac Surgery. J Thorac Cardiovasc Surg 2012. 144(3): 557-62.

Bhat SR, Miyake C, Wang NE. Considerations in the Diagnosis and Emergency Management of Pediatric Tachycardias. Pediatric Emergency Medicine Reports. Volume 17, Number 8, August 2012.

Motonaga KS, Miyake CY, Punn RP, Rosenthal DN, Dubin AM. Insights into Dyssynchrony in Hypoplastic Left Heart Syndrome. Heart Rhythm 2012. 9(12): 2010-5.

Czosek RJ, Bonney WJ, Mah D, Cassedy A, Tanel RE, Imundo JR, Singh AK, Cohen M, Miyake CY, Fawley K, Marino BS. Impact of Cardiac Devices on the Quality of Life in Pediatric Patients and Parents. Circulation Arrhythmia and Electrophysiology 2012. 5(6): 1064-72.

Motonaga KS, Miyake CY, Punn R, Rosenthal DN, Dubin AM. Is there a Role for Cardiac Resynchronization in Pediatric Pulmonary Hypertension? The Journal of Heart and Lung Transplant 2012. 31(4) S29

Char D, Drover DR, Motonaga KS, Gupta SG, Miyake CY, Dubin AM, Hammer GB. The Effects of Ketamine on Dexmedetomidine-Induced Electrophysiologic Changes in Children. Pediatri Anaesth 2013. 23 (10): 898-905.

Harbison AL, Hill AC, Motonaga KS, Miyake CY, Dubin AM. Do Pediatric Electrophysiologists Read Pre-Participation Screening Electrocardiograms More Accurately than General Pediatric Cardiologists? J Pediatr 2013. 163 (6): 1755-1777.

Mah DY, Miyake CY, Sherwin ED, Anderson MJ, Western K, Abrams DJ, Alexander ME, Cecchin F, Walsh EP, Triedman JK. The Use of Integrated Electroanatomic Mapping System and Intracardiac Echocardiography to Reduce Radiation Exposure in Children Undergoing Ablation of Supraventricular Tachycardia. Europace 2014; Feb 16(2):277-83.

Sierh SL, Hanley FL, Reddy VM, Miyake CY, Dubin AM. Incidence and Risk Factors of Complete AV block After Operative VSD Repair. Congenit Heart Dis 2014 May-Jun;9(3):211-5.

Harris BU,Miyake CY, Motonaga KS, Dubin AM. Diagnosis and Management of Pediatric Brugada Syndrome: A Survey of Pediatric Electrophysiologists. Pacing Clin Electrophysiol 2014.May;37(5):638-42.

Kang KT, Potts JE, Radbill AE, La Page MJ, Garnreiter JM. Kubus P, Kantoch MJ, Von Bergen NH, Fournier A, Cote JM, Papagiannis J, Paul T, Anderson CC, Cannon BC, Miyake CY, Blaufox AD Etheridge SP, Sanatani S. Permanent Junctional Reciprocating Tachycardia in Children: A multi-center experience. Heart Rhythm 2014 Aug;11(8):1426-32.

Silva JNA, Erickson CC, Cater CD, Greene A, Kantoch M, Collins KK, Miyake CY, Carboni MP, Rhee EK, Papez A, Bowman TM, Van Hare GF. Management of Pediatric Tachyarrhythmias on Mechanical Support. Circ Arrhythm Electrophysiol 2014 Aug;7(4):658-63.

Mofett BS, Valdes SO, delaUz CM, Miyake C, Kim JJ. Flecainide use in Children with Congenital Heart Disease. Cardiol Young 2014 Sept 12: 1-6. Epub ahead of print.

Moffett BS, Lupo PJ, delaUz CM, Valdes SO, Miyake C, Decker JA, Kim JJ. Efficacy of digoxin in comparison with propranolol for treatment of infant supraventricular tachycardia: analysis of a large, national database. Cardiol Young 2014 Sep 12:1-6.

Respress JL Gershovich PM, Wang T, Reynolds JO, Skapura DG, Sutton JP, Miyake CY, Wehrens XH. Long-term simulated microgravity causes cardiac RyR2 phosphorylation and arrhythmias in mice. Int J Cardiol 2014. Oct 20;176(3): 994-1000.

Yang X, Wang T, Lin X, Yue X, Wang Q, Wang G, Fu Q, Ai X, Chiang DY, Miyake CY ,Wehrens XH, Chang J. Genetic deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling. Circ Res 2015 Jan 2; 116(1):e1-e10.

Barton AL, Moffett BS, Valdes SO, Miyake C, Kim JJ. Efficacy and safety of high-dose propranolol for the management of infant supraventricular tachyarrhythmias. J Pediatr 2015 Jan; 166(1):115-8

Yang P, Moreno JD, Miyake CY, Vaugh-Behrens SB, Jeng M, Wehrens XHT, Noskov S, Clancy CE. In silico prediction of drug therapy in catecholaminergic polymorphic ventricular tachycardia. Accepted for publication. The Journal of Physiology, September 2015.

Dewey FE, Grove ME, Priest JR, Waggott D, Miller CL, Wheeler M, Zia A, Pan C, Karcewski KJ, Miyake CY, Whirl-Carrillo M, Klein TE, Datta S, Altman RB, Snyder M, Quertermous T, Ashley EA. Sequence to medical phenotypes: a framework for interpretation of human whole genome DNA sequence data. Accepted for publication. PLOS genetics, September 2015.

Lalani SR, Pengfei L, Rosenfeld JA, Watkin LB, Chiang T, Ledu MS, Zhu W, Ding Y, Pan S, Miyake CY, Shinawi M, Gambin T, Eldomery M, Adkemir ZHC, Emrick L, Willnai Y, Schelley S, Koenig MK, Memon N, Farach L, Coe BP, Azamian M, Hernandez P, Zapata G, Jhangiani S, Muzny DM, Lotze T, Clark G, Wilfong A, Northrup H, Adesina AM, Bacino C, Scaglia F, Bonnen P, Crosson JE, Maegawa G, Coman D, Inwood A, McGill J, Boerwinkle E, Graham B, Beaudet AL, Eng CM, Hanchard N, Xia F, Orange JS, Gibbs R, Lupski JR, Yang Y. Recurrent muscle weakness with rhabdomyolysis, metabolic crises, and cardiac arrhythmias due to bi-allelic TANGO2 mutations. Accepted, The American Journal of Human Genetics.

Niu MC, Krenek M, Morris S, delauz CM, Pedroza D, Miyake CY, Kim JJ, Valdes SO. Significance of Ventricular Tachycardia in patients with pacemaker Implanted for atrioventricular block. Accepted J Cardiovasc Electrophysiol 2016.

* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.