Amanda B. Grimes, MD

Dr. Amanda Grimes is a specialist in pediatric immune hematology at Texas Children's Cancer and Hematology Center. 

Dr. Grimes is passionate about advancing knowledge and research within her fields of expertise, particularly with the goal of improving therapies and outcomes for patients suffering from immune hematologic and/or lymphoproliferative diseases – specifically: Evans syndrome and immune thrombocytopenia (ITP).

Dr. Grimes cares for patients with blood disorders, specializing in immune-mediated cytopenias including autoimmune neutropenia (AIN), immune thrombocytopenia (ITP), autoimmune hemolytic anemia (AIHA), thrombotic thrombocytopenic purpura (TTP) and Evans syndrome. As a part of the Immune Hematology team, she participates in clinical and translational research aimed at improving the diagnostic and therapeutic management of children with immune-mediated blood disorders. She works closely with inter-disciplinary colleagues in the departments of Immunology, Rheumatology, and Genetics at Texas Children’s Hospital, in order to deliver the best possible care to this group of children.

She has authored a chapter on Evans syndrome in Springer’s “Immune Hematology: Diagnosis and Management of Autoimmune Cytopenias” and several other publications related to better describing and improving outcomes among children with immune-mediated blood disorders.

She is currently participating in both clinical and translational research with her mentor, Dr. Jenny Despotovic, focusing on ITP and Evans syndrome. Their findings regarding both biological and clinical predictors of chronic immune thrombocytopenia have been presented at the annual conferences of the American Society of Hematology (ASH).

Dr. Grimes continues to collaborate with the ITP Consortium of North America (ICON), including a biologic repository for patients with ITP and Evans syndrome across North America, which is located at Baylor College of Medicine and supported by the Research Resources Office IT database management. She serves as the chair for the ITP Consortium of North America’s Biology Committee.

Prior to her current appointment, she completed her fellowship subspecialty training in pediatric hematology-oncology at Baylor College of Medicine, where she was appointed as Chief Fellow for the Cancer and Hematology Center at Texas Children's Hospital.

Board Certifications
American Board of Pediatrics
American Board of Pediatrics - Pediatric Hematology/Oncology
American Board of Internal Medicine

Clinical Interests
Immune hematology (immune thrombocytopenia (ITP), Evans syndrome, autoimmune hemolytic anemia)