ZIC1 gene drives distinct medulloblastoma types in different ways

*Breaking News* Excited to share that a study in Nature Genetics, led by Drs. Michael Taylor at Baylor College of Medicine & Texas Children's Cancer Center, Paul Northcott at St. Jude Children's Research Hospital and L. Frank Huang at Mayo Clinic College of Medicine, reveals that the ZIC1 gene drives different medulloblastoma subgroups through distinct mechanisms.

The findings reveal that ZIC1 mutations in G4 and SHH medulloblastoma tumors operate differently, emphasizing the need for context-specific therapeutic strategies.

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