Pati Lab Pati Lab Team
Over more than two decades, the Pati Lab has shaped how the field understands sister chromatid cohesion and separation — work that established Separase as an oncogene, proposed the "Handcuff" model of cohesin, and identified the first small-molecule inhibitors of Separase. With over 65 peer-reviewed publications, this body of work now underpins our preclinical drug development programs in Ewing sarcoma and breast cancer.
We are a tight-knit, multidisciplinary group that thrives on collaboration, mentorship, and rigorous science. Together, we move ideas from the bench toward the clinic.
Current Members
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Become part of our team!
Join us in turning chromosome biology into the next generation of cancer therapies.
We welcome motivated students, postdoctoral fellows, and collaborators interested in chromosome biology, medicinal chemistry, or translational cancer research. Our lab combines fundamental discovery with active drug development; a rare environment where you can move a finding from mechanism through to a preclinical candidate.
Click below to contact us about joining the Pati Lab.