Jin Xu, PhD
Director of Research and Business Development, Jan and Dan Duncan Neurological Research Institute, Baylor College of Medicine
Languages: English
Office location:
1250 Moursund Street
Houston, TX 77030
Get to know Jin Xu, PhD
Dr. Xu's interests include therapeutic development for neurological diseases.
He supports and promotes the translational research and therapeutic development activities at the Jan and Dan Duncan Neurological Research Institute.
* Texas Children’s Hospital physicians’ licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician’s office and were not verified by Texas Children’s Hospital.
Xu W, Bao P, Jiang X, Wang H, Qin M, Wang R, Wang T, Yang Y, Lorenzini I, Liao L, Sattler R, Xu J "Reactivation of Nonsense-Mediated mRNA Decay Protects Against C9orf72 Dipeptide-Repeat Neurotoxicity." Brain. 2019 May 1;142(5):1349-1364. Pubmed PMID: 30938419
Xu W, Xu J "C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in Drosophila Glutamatergic Neurons." J Neurosci.. 2018 Aug;38(35):7741-7752. Pubmed PMID: 30037833
Xu J, Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C, Yankner BA. "The Parkinson's Disease-Associated DJ-1 Protein Is a Transcriptional Co-Activator That Protects Against Neuronal Apoptosis." Hum Mol Genet.. 2005 May;14(9):1231-41. Pubmed PMID: 15790595
Xu J, Kao SY, Lee FJ, Song W, Jin LW, Yankner BA. "Dopamine-dependent Neurotoxicity of Alpha-Synuclein: A Mechanism for Selective Neurodegeneration in Parkinson Disease." Nat Med.. 2002 Jun;8(6):600-6. Pubmed PMID: 12042811
Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J. "Caspase-12 Mediates Endoplasmic-Reticulum-Specific Apoptosis and Cytotoxicity by Amyloid-Beta." Nature. 2000 Jan;403(6765):98-103. Pubmed PMID: 10638761