Carl E. Allen, MD, PhD

Location

  • Texas Medical Center

Specialty

Cancer
Blood Disorders
Adult Hematology-Oncology

Phone: 832-824-4312
Fax: 832-825-1206

Contact Information

1102 Bates
Suite 750
Houston, TX 77030

Co-Director, Histiocytosis Program
Co-Director, Lymphoma Program

Associate Professor, Department of Pediatrics, Section of Hematology/Oncology, Baylor College of Medicine

Education

School Education Degree Year
Baylor College of Medicine fellowship Pediatric Hematology Oncology 2008
Columbus Children's Hospital - Heart Center residency Pediatrics 2005
Ohio State University College of Medicine and Public Health medical school Doctor of Medicine 2002
Ohio State University College of Medicine and Public Health university Doctor of Philosophy

About Carl Allen

Along with Dr. Kenneth McClain, Dr. Carl Allen has developed the largest Histiocytosis Center in the world with over 100 new diagnoses annually.

Dr. Allen graduated from Ohio State University College of Medicine and Public Health with his medical degree and doctorate of philosophy. He completed his resident at Columbus Children’s Hospital and pediatric hematology-oncology fellowship at Baylor College of Medicine. 

His clinical special interests include: Langerhans cell histiocytosis (LCH), hemophagocytic lymphohistiocytosis (HLH), leukemia, lymphoma and stem cell transplantation. He is board certified by the American Board of Pediatrics in pediatric hematology/oncology. 

 

Organization

Organization Name Role
American Society for Pediatric Hematology/Oncology (ASPHO) Member
American Society of Bone Marrow Transplantation (ASBMT) Member
American Society of Clinical Oncology (ASCO) Member
American Society of Hematology (ASH) Member
Histiocyte Society Member

Research Statement

Dr. Carl Allen's primary research is focused on the clinical and biologic aspects of Langerhans cell histiocytosis (LCH). Along with Dr. Kenneth McClain, Dr. Carl Allen has developed the largest Histiocytosis Center in the world with over 100 new diagnoses annually, allowing the center to create a large bank of LCH tissues and plasma. 

Dr. Allen has developed gene expression and proteomic strategies to analyze the identity and function of the cells that cause LCH. The ultimate goal of these experiments is to identify genes, proteins, and pathways that may be used to diagnose and cure patients with LCH. These experiments may also provide insight into dendritic cell biology and tumor immunology.

Dr. Carl Allen is an associate professor of pediatric hematology-oncology at Baylor College of Medicine (BCM). He is co-director of the Fayez Sarofim Lymphoma Program research laboratory at Texas Children's Cancer and Hematology Centers. Dr. Allen has significant experience in clinical as well as translational research. He is principal investigator of investigator-initiated clinical trials in Hodgkin lymphoma and non-Hodgkin lymphoma, both of which include correlative biology aims. He is national principal investigator of a study to optimize hematopoietic cell transplant in patients with EBV-related lymphoproliferative disorders, through the Blood and Marrow Transplant Clinical Trials Network.

Dr. Allen has an ongoing collaborative research effort with the Uganda Cancer Institute research program, and collects tissue (viably preserved tumor, peripheral blood cells and plasma) and linked clinical data on approximately 25 new endemic Burkitt's Lymphoma cases every quarter from Uganda.

Research Interests
Langerhans Cell Histiocytosis (LCH)
Hemophagocytic Lymphohistiocytosis (HLH)
Lymphoma
Tumor Immunology
Lymphocyte Development
Dendritic Cell Biology

Selected Publications

Related Videos

  • Embedded thumbnail for Q&A: What is histiocytosis?
    Q&A: What is histiocytosis?
  • Embedded thumbnail for Histiocytosis: A Comprehensive Overview with Texas Children’s Cancer Center
    Histiocytosis: A Comprehensive Overview with Texas Children’s Cancer Center