ACCESS - Adolescent and Childhood Cancer Epidemiology and Susceptibility Service
Adolescent and Childhood Cancer Epidemiology and Susceptibility Service (ACCESS) for Texas
The purpose of this core facility is to collect biological samples from children with cancer and collect DNA from the parents of children with cancer, children without cancer, or parents of children without cancer to gain a better understanding of how childhood cancers develop.
The parents of children with cancer will also complete a risk factor questionnaire about exposures that the child or parents may have had in the past.
There are no restrictions on the types of cancers to be enrolled; however, the numbers of each cancer in ACCESS will reflect the incidence in Texas. In addition to blood or saliva samples collected for DNA analyses, plasma samples at several time points during therapy are also being collected. Associated epidemiological and clinical data can be linked to the samples to provide a rich resource for studying the risk factors for childhood cancers.
Study Sites
Texas Children’s Hospital, Houston, TX
CHRISTUS Children’s, San Antonio, TX
Children’s Medical Center of Dallas, Dallas, TX
Vannie E. Cook Jr. Children’s Cancer and Hematology Clinic, McAllen, TX
El Paso Children’s, El Paso, TX
Covenant Children’s & University Medical Center, Lubbock, TX
Northwest Texas Children’s Hospital, Amarillo, TX
Cook Children’s Medical Center, Fort Worth, TX
Enrolled Participants and Biospecimens Collected
To date, ACCESS has enrolled more than 6,000 participants across its network of Texas sites, with 15,777 biospecimens collected. The figures below summarize enrollment by cancer type, race/ethnicity, and biospecimen type.
Funding
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This study is supported by the Cancer Prevention and Research Institute of Texas under award numbers RP160771, RP210064.
Contact Us
Scientists who are interested in utilizing the data and/or specimens being collected through ACCESS are encouraged to contact the study team at epicenter@bcm.edu with a brief description of the proposed project. The project will be reviewed for feasibility and scientific merit by the Steering Committee (composed of the ACCESS Investigators listed below):
Dimarys Sanchez, MD
Baylor College of Medicine CHRISTUS Children’s
Laura Klesse, MD, PhD
UT Southwestern Children’s Medical Center Dallas
S. Taha Muntajibuddin, MD
Cook Children’s Medical Center
Benjamin Carcamo, MD
TTUHSC-El Paso El Paso Children’s Hospital
Mohamad Al-Rahawan, MD
TTUHSC - Lubbock Covenant Children’s Hospital, Lubbock University Medical Center
Smita Baskaran, MD
TTUHSC - Amarillo Northwest Texas Children’s Hospital
