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Our investigators play leadership roles at the national level through participation in the solid tumor clinical research efforts of the National Cancer Institute-sponsored Children’s Oncology Group (COG). We use translational research to initiate clinical trials. Examples of these include:
- promising phase I vaccine trials in the management of neuroblastoma
- engineered T cell therapy for osteosarcoma.
Our comprehensive program also focuses on the genetic composition of osteosarcoma and potential of osteosarcoma cells to spread to distant organs. We are also examining how genome sequencing can eventually lead to better outcomes for children with solid tumors.