Holly K. Harris, MD

Personal Statement

I am committed to providing family-centered and evidence-based care for children with neurodevelopmental challenges. I enjoy discovering each child’s unique strengths while also aiding the patient and family in navigating any challenges or uncertainty that may accompany a neurodevelopmental diagnosis. Along with providing diagnostic evaluations and ongoing care if needed, I am additionally invested in research, seeking to broaden our understanding of these diagnoses in order to best care for patients. I see patients for diagnostic assessments at the Meyer Center for Developmental Pediatrics and Autism and serve as Director of the Fragile X Clinic at the Meyer Center.

Clinical Interests:

Autism spectrum disorder, Fragile X Syndrome, intellectual disability, ADHD, learning disabilities, anxiety, genetic and metabolic disorders, behavioral concerns, prematurity

Research Interests:

My research interest is in autism spectrum disorder, and specifically I seek to better understand the heterogeneity seen in children with autism. I do this through both clinical and translational projects. I am interested in determining if specific patient characteristics or symptoms cluster together to define subgroups within the broader autism spectrum, and if so, whether those subgroups might aid in our understanding of causes or inform best treatments. I also have in interest in translational collaboration with scientists in the fields of genetics and neurology as we seek to better understand the etiology of autism spectrum disorders.  I am involved in multiple collaborative research endeavors with colleagues at the Neurologic Research Institute. As director of the Fragile X Clinic, I am also involved in national research efforts related to Fragile X Syndrome.

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* Texas Children’s Hospital physicians’ licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician’s office and were not verified by Texas Children’s Hospital.

Harris HK, Lee C, Sideridis GD, Barbaresi WJ, Harstad E. Identifying Subgroups of Toddlers with DSM-5 Autism Spectrum Disorder Based on Core Symptoms. J Autism Dev Disord. 2021 Jan 28. doi: 10.1007/s10803-021-04879-z. PMID 33507459

Harris HK, Nakayama T, Lee, J et al. Disruption of RFX family transcription factors causes autism, attention-deficit/hyperactivity disorder, intellectual disability, and dysregulated behavior. Genet Med. (2021). https://doi.org/10.1038/s41436-021-01114-z.

Harris HK, Sideridis GD, Barbaresi WJ, Harstad E. Pathogenic Yield of Genetic Testing in Autism Spectrum Disorder. Pediatrics. September 2020:e20193211. doi:10.1542/peds.2019-3211.

Marcus CH, Newman LR, Winn AS, Antanovich K, Audi, Z, Cohen A, Hirsch AW, Harris HK, Miller KA, Michelson CD. TEACH and repeat: Deliberate practice for teaching. The Clinical Teacher. July 2020; 17: 688-694

Hodges H, Fealko C, Soares N. Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation  Translational Pediatrics 2020; 9 (suppl. 1): S55-65.

Weissman, L and Harris H. Autism spectrum disorder in children and adolescents: Complementary and alternative therapies. In: UpToDate, Post, TW (Ed), UpToDate, Waltham, MA, 2014.

Shagrin, B, Callas, C, McFee, A, Fantasia, K, Wolbrink, T, Hodges, H. Developmental Milestones. 12/2018. Online video. OPENPediatrics. https://www.openpediatrics.org/assets/video/developmental-milestones (private video).

Hodges HK, Lee PY, Hausmann JS, Teot LA, Sanford EL, Levin KW. “Hypercalcemia and Miliary Sarcoidosis in a 15 Year Old Boy.” Arthritis and Rheumatism 2013 Aug;65(8):2112.