Angelman Syndrome Clinic

<p>Angelman Syndrome Clinic</p>

Internationally recognized expertise in Angelman syndrome care

Texas Children’s Hospital offers highly specialized care for children who have Angelman syndrome, a genetic disorder that affects brain development, causing problems with movement, learning, speech and other issues. Our Angelman Syndrome Clinic is one of only a few in the country — and the first in Texas — that focuses exclusively on this complex genetic disorder.

What is Angelman syndrome?

Angelman syndrome is a neurogenetic disorder, which is a condition of the brain, spinal cord, nerves and muscles that’s caused by genetic mutations (changes). This disorder results from a change in the UBE3A gene, which most often happens randomly around the time of conception. In very rare cases, the gene change can be inherited (passed from parent to child).

Children who have Angelman syndrome typically have happy, excitable personalities, with frequent smiling and laughing. However, they experience development delays, learning disabilities, severe speech impairment and problems with balance and movement. Other possible signs of Angelman syndrome include small head size, difficulty feeding, sleep disorders and seizures.

Multidisciplinary team for complete Angelman syndrome care under one roof

Since 2018, the Angelman Syndrome Clinic has brought hope to children and their families affected by this rare genetic disorder. At our clinic, you and your child can see all the specialists they need in one location.

Our clinic brings together a team from multiple specialties with expertise in Angelman syndrome and the challenges it presents. At Texas Children’s, your child has access to highly specialized care from doctors and providers in:

  • Genetics and genetic counseling
  • Neurology
  • Psychiatry and psychology
  • Developmental and behavioral pediatrics
  • Physical medicine and rehabilitation, including physical, occupational and speech-language therapies
  • Nutrition
  • Social work