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Texas Medical Center

Phone: 832-824-4232


1102 Bates Ave., Ste. C.750.12-D
Houston, TX 77030

Research Laboratory

Xin Xu, PhD, MS, M(ASCP)

Assistant Professor, Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine


School Education Degree Year
Baylor College of Medicine Post-doctoral Fellow Microbiology and Cell Biology 2018
Universität Osnabrück PhD Doctor of Philosophy, Microbiology 2014
North East Normal University Masters Master of Science, Biochemistry and Molecular Biology 2004


Organization Name Role
American Association of Immunologists (AAI) Member
American Society of Gene and Cell Therapy (ASGCT) Member

Research Statement

Dr. Xin Xu is a formally-trained microbiologist with extensive experience in translational research. His postdoctoral research focused on development of an innovative salmonella-based cancer vaccine platform that is currently being submitted as the subject of an Investigational New Drug (IND) application with the goal of clinical evaluation.

His pre-clinical work showed that the vaccine induces potent anti-tumor activity and long-term protective immune memory in mice (Xu et al., Cancer Research). These studies have been awarded with highly competitive grants from The Cancer Prevention and Research Institute of Texas (CPRIT), the Leukemia & Lymphoma Society, and the V Foundation and led to IND submission for phase 1 clinical trial of a salmonella-based cancer vaccine in patients with multiple myeloma.

Within the Metelitsa group, he has conducted correlative studies on patient samples from our recently initiated first-in-human CAR NKT cell clinical trial in children with neuroblastoma (NCT03294954). He is also exploring translational methods to improve the persistence and efficacy of CAR NKT immunotherapy.

Technologist in Microbiology
American Society for Clinical Pathology

Selected Publications

Awards & Honors

2018   AAI Trainee Award and oral presentation, American Association of Immunologists (AAI)
2017  20th Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT)
2014  Texas Children’s Cancer and Hematology Center, 10th Annual Research Symposium

* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.