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MRKH Center | Mayer-Rokitansky-Küster-Hauser Syndrome

<p>MRKH Center | Mayer-Rokitansky-Küster-Hauser Syndrome</p>

Offering Care and Support for Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome

Advanced treatment for Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome

Texas Children’s MRKH Center provides comprehensive lifelong care and support for young women diagnosed with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, which is a congenital condition that affects the female reproductive system and is characterized by an underdeveloped vagina and uterus. 

Our center provides education about the diagnosis from experts in pediatric and adolescent gynecology, genetics and psychology. Our interdisciplinary team also includes specialists in maternal–fetal medicine, reproductive endocrinology and infertility, and transplant surgery.

The MRKH Center offers multiple treatment options, ranging from dilation and vaginal lengthening to surgery. Uterine remnant management and endometriosis care to control pelvic pain symptoms may be required. 

Life after diagnosis may feel overwhelming and uncertain, but our team is here to answer questions, provide guidance and connect our patients with resources and specialists. 

What is Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome?

Mayer–Rokitansky–Küster–Hauser (MRKH) Syndrome is a condition present at birth in which parts of the female reproductive system – such as the uterus, cervix and upper vagina – do not develop as expected. 

MRKH is usually diagnosed during adolescence, often when menstruation does not begin (a condition called primary amenorrhea). The exact cause of MRKH is not fully known, but both genetic and environmental factors may play a role.

Why Texas Children’s

MRKH experts

Our team includes fellowship-trained experts in pediatric and adolescent gynecology, pediatric genetics, reproductive genetics, pediatric radiology, psychology and other specialties who manage all aspects of MRKH from diagnosis to management throughout a woman’s reproductive life.

Meet the Team

Unique treatment options

Our Pavilion for Women team is studying uterus transplantation as a treatment option to help women achieve healthy pregnancies. Very few centers worldwide offer this innovative option.

Learn more

Commitment to research

We’re committed to leading research to better understand the long-term and genetic implications of MRKH, informing patients about supportive advocacy organizations such Beautiful You MRKH and offering the latest treatment options available.

See treatments

What to Expect for Your First Visit 

Our MRKH coordinator can help you schedule your initial appointment and can assist with coordinating any follow-up visits.

During your first visit, you can expect to:

  • Meet our care team and learn about the support we provide
  • Have a physical exam and, if needed, have additional tests ordered
  • Ask questions – we’re here to guide and support you every step of the way

If all testing has already been completed prior to your visit:

  • We will review your results, talk through your diagnosis, and provide helpful information and resources to support you. 

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