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Uterus Transplant Research Program

Texas Children’s Pavilion for Women Uterus Transplant Research Program

Nearly 1 in 4,000 women have a condition known as absolute uterine factor infertility (AUFI), a congenital or surgical absence of a uterus or the presence of a nonfunctional uterus making childbirth impossible.

Until 2014, the only option for women affected by AUFI was adoption or surrogate motherhood. Now, some women may benefit from a uterus transplant to treat AUFI. Approximately 80 uterus transplants have been performed worldwide, with more than 50 occurring within the past three years.


Program overview

Through the Texas Children’s Hospital Uterus Transplant Research Program, our investigators are studying uterus transplantation as a treatment option for women with AUFI to help them achieve healthy pregnancies. Our goal is to offer our patients innovative, groundbreaking care consistent with the breadth of our expertise.

Texas Children’s leads the fields of transplant surgery, reproductive endocrinology and infertility, and high-risk pregnancy through innovation, multidisciplinary collaboration and excellence in patient care, education and research.

Our expert team works to achieve the following goals for each uterus transplant research participant:

  • Safely procure a viable uterus for transplantation.
  • Transplant the donated uterus to achieve menstrual cycles.
  • Establish pregnancy in the recipient via in vitro fertilization.
  • Successfully deliver a safe live birth (at 23 or more weeks gestation).

Participants in the Uterus Transplant Research Program receive state-of-the-art care through Texas Children’s Pavilion for Women, which includes the renowned Texas Children’s Fetal Center®, the Division of Maternal-Fetal Surgery, The Menopause Center, The Family Fertility Center and The Women’s Place (for reproductive psychiatry). The Pavilion for Women is a designated Level IV maternal care facility and features a Level IV neonatal intensive care unit — the highest level of care available.

The Pavilion for Women’s resources are complemented by patient care areas in the renowned Legacy Tower, including state-of-the-art operating and recovery suites, acute care units and the hospital-based Maternal-Fetal Center outpatient unit, which serves pregnant women with highly complicated conditions in an ambulatory setting.

If you are interested in becoming a uterus transplant donor or recipient, please click here.