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K12 Pediatric Oncology Research Training Program Epidemiology and Survivorship Research Track

Scholars in the Epidemiology and Survivorship Pathway will primarily conduct their laboratory and clinical research under the mentorship of investigators in our Center for Epidemiology and Population Health. Researchers in the Center for Epidemiology and Population Health use population-based approaches for addressing susceptibility, disparities, and outcomes among children with cancer and hematologic conditions. This research group has strong collaborations across Texas Children's Cancer Center, including the other Clinical Research Pathways proposed in this K12 application and across Baylor College of Medicine (e.g., Center for Environmental Precision Health and Human Genome Sequencing Center).

Scholars participating in this Pathway will have access to several unparalleled resources, including but not limited to:

  • the Reducing Ethnic Disparities in Acute Leukemia (REDIAL) Consortium,
  • the Genetic Overlap between Anomalies and Cancer in Kids (GOBACK) study,
  • Childhood Cancer and Leukemia International Consortium (CLIC),
  • CEPH-led ancillary studies in the Childhood Cancer Survivorship Study (CCSS),
  • Survivorship and Access to Care for Latinos to Address and Understand Disparities (SALUD), and
  • The Adolescent and Childhood Cancer Epidemiology and Susceptibility Service (ACCESS) for Texas.

Scholars utilizing these resources are mentored in all steps of population-based approaches to biomedical research.

Objectives

The overall objectives of the Epidemiology and Survivorship Clinical Research Pathway are to:

  1. Develop expertise in clinical research methodology including design, implementation, monitoring, and analysis of population-based and epidemiologic studies of childhood cancer susceptibility and survivorship.
  2. Understand the risk factors contributing to childhood cancer susceptibility and adverse outcomes in survivorship.
  3. Develop expertise in the integration of -omics technologies in population-based and epidemiologic clinical research studies of childhood cancer susceptibility and survivorship.
  4. Acquire an understanding of and expertise in the development of population-based and epidemiologic clinical research studies to address and understand cancer health disparities.
  5. Understand the development of multi-institutional epidemiologic studies of childhood cancer susceptibility and survivorship.
  6. Understand the ethical and regulatory issues involved in clinical epidemiologic studies of childhood cancer susceptibility and survivorship, including special research protections afforded to children, appropriate recruitment of minorities into research studies, and the role of the IRB and other regulatory agencies.

Epidemiology and Survivorship Research Track Mentor

Philip J. Lupo, PhD, MPH

Phillip Lupo, PhD, MPH - Track Director, Epidemiology and Survivorship
Endowed Chair in Molecular Epidemiology, Texas Children's Hospital
Director, Epidemiology and Population Sciences Program, Texas Children's Cancer and Hematology Center
Professor, Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine
Member, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine
Adjunct Associate Professor, Human Genetics Center, Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health

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