Collaborate with us Clinical

In the paper titled "Association of Secondary Mitral Regurgitation and Right Ventricular Dysfunction among Patients with Non-Ischemic Cardiomyopathy," Tayal et al. aimed to investigate the relationship between secondary mitral regurgitation (MR) and right ventricular (RV) dysfunction in heart failure patients with non-ischemic cardiomyopathy (NICM) using cardiac magnetic resonance (CMR). In a cohort of 241 NICM patients enrolled between 2008 and 2019, MR severity and RV function were quantified. RV dysfunction, defined as an RV ejection fraction (RVEF) <45%, was found in 61% of patients. Those with RV dysfunction had significantly higher median MR volume and MR fraction compared to those without RV dysfunction. Secondary MR was independently associated with RV dysfunction, with higher MR volume and fraction linked to increased odds of RV dysfunction. Additionally, an increase in RVEF was independently associated with a lower risk of adverse events. These findings suggest that in NICM patients, the severity of secondary MR is strongly linked to the prevalence of RV dysfunction, and RV dysfunction correlates with both the severity of LV dysfunction and secondary MR. This study was published in European Heart Journal Cardiovascular Imaging in May 2024.