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Texas Medical Center

Phone: 832-822-2100
Fax: 832-825-4294


6701 Fannin Street
Suite 1560
Houston, TX 77030

V. Reid Sutton, MD

Chief of Service, Metabolic Genetics Clinic
Director, Inborn Errors of Metabolism Service

Professor, Department of Molecular and Human Genetics, Baylor College of Medicine


School Education Degree Year
Baylor College of Medicine Fellowship Molecular & Human Genetics 1999
Washington University School of Medicine Residency Pediatrics 1996
Washington University School of Medicine Internship Pediatrics 1993
University of Kentucky Medical School Doctor of Medicine 1992


I believe in partnering with patients and families to provide quality care that meets an individual’s needs and treatment goals.

Clinical Interests:

Inborn errors of metabolism & Skeletal dysplasias

Research Interests:

Osteogenesis imperfecta, metabolomic profiling for diagnosis and management of inborn errors of metabolism, White-Sutton syndrome, Robinow syndrome, creatine transporter deficiency, gene discovery and syndrome delineation 

View News Articles:

The boy was dying. Zebrafish helped save his life 


Organization Name Role
Accreditation Council for Graduate Medical Education Board of Directors
Baylor Genetics Laboratory Director Biochemical Genetics & Metabolomic Assisted Pathway Screening
Osteogenesis Imperfecta Foundation Medical Advisory Council
Society for Inherited Metabolic Disorders Board of Directors
White-Sutton Syndrome Foundation Medical Advisory Board

Selected Publications

Tosi LL, Floor MK, Dollar CM, Gillies AP; Members of the Brittle Bone Disease Consortium, Hart TS, Cuthbertson DD, Sutton VR, Krischer JP. Assessing disease experience across the life span for individuals with osteogenesis imperfecta: challenges and opportunities for patient-reported outcomes (PROs) measurement: a pilot study. Orphanet Journal of Rare Diseases 14(1):23, 2019, PMID 30696467.

Wangler MF, Hubert L, Donti TR, Ventura MJ, Miller MJ, Braverman N, Gawron K, Bose M, Moser AB, Jones RO, Rizzo WB, Sutton VR, Sun Q, Kennedy AD, Elsea SH. A metabolomic map of Zellweger spectrum disorders reveals novel disease biomarkers. Genetics in Medicine 20(10):1274-1283, 2018 PMID 29419819.

White JJ, Mazzeu JF, Coban-Akdemir Z, Bayram Y, Bahrambeigi V, Hoischen A, van Bon BWM, Gezdirici A, Gulec EY, Raymond F, Touraine R, Thevenon J, Shinawi M, Bever E, Heeley J, Hoover-Fong J, Durmaz CD, Karabulut HG, Marzioglu-Ozdemir E, Cayir A, Duz MB, Seven M, Price S, Ferreira BM, Vianna-Morgante AM, Ellard S, Parrish A, Stals K, Flores-Daboub J, Jhangiani SN, Gibbs RA; Baylor-Hopkins Center for Mendelian Genomics, Brunner HG, Sutton VR, Lupski JR, Carvalho CMB. WNT signaling perturbations underlie the genetic heterogeneity of Robinow syndrome. American Journal of Human Genetics 102(1):27-43, 2018 PMID 29276006.

Jiang Y, Almannai M, Sutton VR, Sun Q, Elsea SH. Quantitation of phenylbutyrate metabolites by UPLC-MS/MS demonstrates inverse correlation of phenylacetate:phenacetylglutamine ratio with plasma glutamine levels. Molecular Genetics & Metabolism 122(3):38-45, 2017.

Duerrschmid C, He Y, Wang C, Li C, Bournat JC, Romere C, Saha PK, Lee ME, Phillips KJ, Jain M, Jia P, Zhao Z, Farias M, Wu Q, Milewicz DM, Sutton VR, Moore DD, Butte NF, Krashes MJ, Xu Y, Chopra AR. Asprosin is a centrally acting orexigenic hormone. Nature Medicine 23(12):1444-1453, 2017 PMID 29106398.

Eldomery MKI, Akdemir ZC, Vögtle FN, Charng WL, Mulica P, Rosenfeld JA, Gambin T, Gu S, Burrage LC, Al Shamsi A, Penney S, Jhangiani SN, Zimmerman HH, Muzny DM, Wang X, Tang J, Medikonda R, Ramachandran PV, Wong LJ, Boerwinkle E, Gibbs RA, Eng CM, Lalani SR, Hertecant J, Rodenburg RJ, Abdul-Rahman OA, Yang Y, Xia F, Wang MC, Lupski JR, Meisinger C, Sutton VR. MIPEP recessive variants cause a syndrome of left ventricular non-compaction, hypotonia and infantile death. Genome Medicine 8(1):106, 2016.

White J, Beck CR, Harel T, Posey JE, Jhangiani SN, Tang S, Farwell KD, Powis Z, Mendelsohn NJ, Baker JA, Pollack L, Mason KJ, Wierenga KJ, Arrington DK, Hall M, Psychogios A, Fairbrother L, Walkiewicz M, Person RE, Niu Z, Zhang J, Rosenfeld JA, Muzny DM, Eng C, Beaudet AL, Lupski JR, Boerwinkle E, Gibbs RA, Yang Y, Xia F, Sutton VR. POGZ truncating alleles cause syndromic intellectual disability. Genome Medicine 8(1):3, 2016.

View Google Scholar Publications


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* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.