Sarah E. Sartain, MD


  • Texas Medical Center


Blood Disorders

Phone: 832-822-4362

Contact Information

6701 Fannin St., Ste. 1580
Houston, TX 77030
United States

Research Area

  • Hemostasis and Thrombosis

Acting Co-Director, Hemostasis and Thrombosis Program
Assistant Professor, Department of Pediatrics, Section of Hematology/Oncology, Baylor College of Medicine


School Education Degree Year
Baylor College of Medicine fellowship Pediatric Hematology/Oncology 2015
Boston Children’s Hospital/Boston Medical Center, Harvard Medical School and Boston University School of Medicine residency Pediatrics 2012
Boston Children’s Hospital/Boston Medical Center, Harvard Medical School and Boston University School of Medicine internship Pediatrics 2010
Tulane University School of Medicine medical school Medical Degree 2009
Emory University bachelors Bachelor of Science, Neuroscience and Behavioral Biology 2005


Dr. Sarah Sartain is the acting co-director of the Hemostasis and Thrombosis Program at Texas Children’s Hospital. Her main focus lies in treating children with disorders of bleeding and clotting. She developed her interest in this field of hematology during her fellowship training at Texas Children’s Hospital when she observed that hospitalized children are at greatest risk for throwing off the delicate balance of the coagulation system, leading to problems with bleeding and clotting. She enjoys interfacing with all other services of the hospital in treating patients with these disorders. Furthermore, she finds diagnosing and treating the most complex disorders of hemostasis and thrombosis in hospitalized children to be a compelling challenge and enjoys following her patients long-term in the outpatient clinic.

According to Dr. Sartain, this is an exciting and pivotal time in the field of pediatric hemostasis and thrombosis. Recent published data has shown efficacy and safety of the direct oral anticoagulants for the treatment of blood clots. These drugs promise to improve the quality of life of children with thrombosis, as they can be taken by mouth and do not require frequent blood-test monitoring.

Most importantly, Dr. Sartain has an intense research interest in clotting disorders and performs research in a basic science laboratory to answer important and unknown clinical questions. She regularly brings difficult patient questions to the laboratory so she may investigate the molecular mechanisms of disease, with the goal improving the care and treatment of children with blood clots. 

Board Certifications
American Board of Pediatrics
American Board of Pediatrics - Pediatric Hematology/Oncology


Organization Name Role
American Society of Hematology (ASH) Member
American Society of Pediatric Hematology/Oncology (ASPHO) Member
Hemostasis and Thrombosis Research Society (HTRS) Member

Research Statement

Dr. Sartain’s current research investigates the interaction between inflammation and the immune system in blood vessel damage and blood clot formation. She is specifically interested in a group of devastating clotting disorders known as thrombotic microangiopathy (TMA), which have high morbidity and mortality rates in children. In a laboratory at nearby Rice University where she is an Adjunct Assistant Professor, she studies the role of part of the immune system known as the alternative complement pathway in causing these disorders. In her lab, she has developed a mouse model of inflammatory TMA with the long-term goal of developing therapies to prevent and treat these disorders, ultimately improving the quality of life and survival of patients with TMA.


2014, HTRS Mentored Research Award

2016, Baylor Pediatric Pilot Award

2019, ASH Scholar Award