Skip to main content

Virtual visit appointments available 7 days a week from 9:00am to 11:00pm. Learn More

COVID-19 Updates

COVID-19 Updates: Get the latest on vaccine information, in-person appointments, virtual visits and more. Learn More


Texas Medical Center

Cancer and Hematology, Adult Hematology-Oncology
Phone: 832-822-4208
Fax: 832-825-1503


6701 Fannin St., Ste. 1510.11
Houston, TX 77030

Research Laboratory

Research Area

Kenneth L. McClain, MD, PhD

Director, Histiocytosis Program
Director, Pediatric Lymphoma-Histiocytosis Fellowship Program
Professor, Department of Pediatrics, Section of Hematology/Oncology, Baylor College of Medicine


School Education Degree Year
University of Minnesota Medical School at Minneapolis Fellowship Hematology-Oncology 1981
National Institutes of Health Fellowship Molecular & Human Genetics 1979
Johns Hopkins University School of Medicine Residency Pediatrics 1976
Johns Hopkins University School of Medicine Internship Pediatrics 1974
University of Chicago, Pritzker School of Medicine Medical School Doctor of Medicine 1973
University of Chicago, Pritzker School of Medicine University Doctor of Philosophy 1972


Dr. Kenneth McClain is Director of the Histiocytosis Program at Texas Children’s Cancer and Hematology Center and a member of the leukemia and lymphoma programs. Dr. McClain and Dr. Carl Allen see 150 newly-diagnosed patients with a variety of histiocytic diseases each year and follow more than 1,000 active patients, including patients from five continents.

His clinical interests include: hematologic disorders, leukemia, lymphoma, histiocytosis, and sickle cell disease.

Board Certifications
American Board of Pediatrics - Pediatrics
American Board of Pediatrics - Pediatric Hematology/Oncology


Organization Name Role
American Society of Hematology (ASH) Member
American Society of Pediatric Hematology/Oncology (ASPHO) Member
Current Reviews in Pediatrics Editorial Board, 2004-Present
Gulf Coast Hematology Society (GCHS) Past-President
Histiocyte Society Past-President
Histiocytosis Association of America (HAA) Board Member
PDQ Pediatric Treatment Editorial Board 2006 - Present
Society for Pediatric Research Member, 1986-Present

Research Statement

Dr. Kenneth McClain's research is focused on the clinical and biologic aspects of Langerhans cell histiocytosis (LCH). He is a key member of the clinical trials group of the Histiocyte Society. A number of clinical studies are in progress or development including new therapeutic interventions for CNS LCH. Current biologic studies in his lab are focused on determining the gene expression profiles Langerhans cells and lymphocytes from control and patient tissues and making clinical correlations.

Research Interests
Clinical and biologic aspects of Langerhans cell histiocytosis (LCH)
Gene expression profiles

Awards & Honors

2019: George R. Buchanan Lectureship Award, American Society of Pediatric Hematology/Oncology
2009: Who's Who
2005-2009: Texas Super Doctor
2003-2009: Best Doctor
2007: Nesbit Prize for Best Clinical Paper. 23rd Annual Histiocyte Society Meeting, Cambridge England
2005-2006: Texas Super Doctor
2004: Montclair Who’s Who in Healthcare
2003-2008: Best Doctors in America
2002: Visiting Professor of Pediatrics. McGill University. 
2002: Ph.D. Thesis Opponent. The Karolinska Institute, Stockholm Sweden
2000-2003: President, Histiocyte Society
2000: Who’s Who
1996: Visiting Professor of Pediatrics, Charles University, Second Medical Faculty, Motol, Prague, Czech Republic, Conferred
1998-2001: Editorial Board, Medical and Pediatric Oncology

AcademicKeys Who’s Who in Medical Sciences



Latest Videos

* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.