Kenneth L. McClain, MD, PhD


  • Texas Medical Center


Blood Disorders
Adult Hematology-Oncology

Phone: 832-822-4208
Fax: 832-825-1503

Contact Information

6701 Fannin
Suite 1510.11
Houston, TX 77030
United States

Director, Histiocytosis Program
Director, Pediatric Lymphoma-Histiocytosis Fellowship Program

Professor, Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine


School Education Degree Year
University of Minnesota Medical School at Minneapolis fellowship Hematology-Oncology 1981
National Institutes of Health fellowship Molecular & Human Genetics 1979
Johns Hopkins University School of Medicine residency Pediatrics 1976
Johns Hopkins University School of Medicine internship Pediatrics 1974
University of Chicago, Pritzker School of Medicine medical school Doctor of Medicine 1973
University of Chicago, Pritzker School of Medicine university Doctor of Philosophy 1972


Dr. Kenneth McClain is Director of the Histiocytosis Program at Texas Children’s Cancer and Hematology Centers and a member of the leukemia and lymphoma programs. Dr. McClain and Dr. Carl Allen see 100 new patients with a variety of histiocytic diseases each year. His clinical interests include: hematologic disorders, leukemia, lymphoma, histiocytosis, and sickle cell disease.

Board Certifications

American Board of Pediatrics: Pediatrics and Pediatric Hematology/Oncology


Organization Name Role
American Society of Hematology (ASH) Member
American Society of Pediatric Hematology/Oncology (ASPHO) Member
Gulf Coast Hematology Society (GCHS) Past-President
Histiocyte Society Past-President
Histiocytosis Association of America (HAA) Board Member

Research Statement

His research is focused on the clinical and biologic aspects of Langerhans cell histiocytosis (LCH). He is a key member of the clinical trials group of the Histiocyte Society. A number of clinical studies are in progress or development including new therapeutic interventions for CNS LCH. Current biologic studies in his lab are focused on determining the gene expression profiles Langerhans cells and lymphocytes from control and patient tissues and making clinical correlations.

Research Interests

Clinical and biologic aspects of Langerhans cell histiocytosis (LCH)
Gene expression profiles

Selected Publications


Society for Pediatric Research, 1986-Present
Visiting Professor of Pediatrics, Charles University, Second Medical Faculty, Motol, Prague, Czech Republic, Conferred 1996.
President, Histiocyte Society 1998-2001 Editorial Board, Medical and Pediatric Oncology 2000-2003
Visiting Professor of Pediatrics. McGill University. April 15-18, 2002
Ph.D. Thesis Opponent. The Karolinska Institute, Stockholm Sweden. May 17, 2002
Selected as one of Best Doctors in America 2003-2008
Texas Super Doctor 2005-2006
Editorial Board: Current Reviews in Pediatrics 2004-Present
AcademicKeys Who’s Who in Medical Sciences

2004 Montclair Who’s Who in Healthcare
PDQ Pediatric Treatment Editorial Board 2006-Present
Nesbit Prize for Best Clinical Paper. 23rd Annual Histiocyte Society Meeting Cambridge England, September 23-25, 2007
Who’s Who 2000, 2009
Best Doctor 2003-2009
Texas Super Doctor 2005-2009

Related Videos

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    Q&A: What is histiocytosis?
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    Histiocytosis: A Comprehensive Overview with Texas Children’s Cancer Center