Daniel H. Leung, MD

Location

  • Texas Medical Center

Specialty

Gastroenterology, Hepatology and Nutrition

Phone: 832-822-3131
Fax: 832-825-4131

Contact Information

6701 Fannin Street
Suite 1100
Houston, TX 77030
United States
Texas

Director, Pediatric Hepatology and Liver Transplant Medicine

Texas Children's Hospital


Associate Professor of Pediatrics, Baylor College of Medicine

Education

School Education Degree Year
Children's Hospital of Philadelphia fellowship Pediatric Gastroenterology 2009
Baylor College of Medicine residency Pediatrics 2006
University of Texas School of Medicine at San Antonio medical school Doctor of Medicine 2003

About

Dr. Daniel H. Leung is an Associate Professor of Pediatrics within the Division of Gastroenterology, Hepatology, and Nutrition at Baylor College of Medicine where he serves as Director of Pediatric Hepatology and Liver Transplant Medicine and the Director of the Viral Hepatitis Program at Texas Children's Hospital. He is a clinician-scientist with broad expertise in the field of pediatric hepatology who has devoted his career to the study and care of children with chronic fibroinflammatory and cholestatic liver diseases and as Director of Clinical Research within the Division of Gastroenterology, Hepatology and Nutrition from 2016-2019. He has unique expertise in the areas of liver fibrosis, biomarker indices within pediatric liver disease, and pediatric portal hypertension (See interview at https://aasldpubs.onlinelibrary.wiley.com/hub/journal/20462484/video/9-5-interview-leung and has helped spearhead a translational NIH-funded collaboration in the area of fibrosis biomarkers (5U01 DK103149-04S, Clinical Center for ChiLDREN: Pathogenesis, Biomarkers, and Antifibrotic Therapy) which he oversees within the parent ChiLDReN FORCE study (FibroScan™ in Pediatric Cholestatic Liver Disease). Dr. Leung is also devoted to the cure and treatment of children affected by hepatitis B and C and cystic fibrosis-related (CF) gastrointestinal and liver disease. He served as Lead Co-Principal Investigator for a multi-center observational longitudinal study of infants diagnosed with CF by newborn screening (BONUS) funded by the Cystic Fibrosis Foundation and has been the center Principal Investigator for the NIH funded Cystic Fibrosis Liver Disease (CLFD) Network: Prediction by Ultrasound of the risk of Hepatic Cirrhosis in CF (PUSH) study since 2010. Dr. Leung is board certified by the American Board of Pediatric Gastroenterology, Hepatology, and Nutrition and a Fellow of the American Association of the Study of Liver Diseases.

Organization

Organization Name Role
American Association for the Study of Liver Diseases Training Chair, Pediatric SIG Steering Committee 2013-2016 Vice Chair, 2019
American Liver Foundation Board of Directors, President (2013-2018)
North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Member, Hepatology Committee 2010-2013

Publication

Leung, DH, W Klish et al. Age and ethnic-specific elevation of ALT among obese children at risk for NASH: Implications for Screening. Clinical Pediatrics 2009, Jan; 48(1):50-7  PMID 18832535.

Mack CL, Gonzalez-Peralta RP, Gupta N, Leung D, Narkewicz MR, Roberts EA, Rosenthal P, Schwarz KB.  North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Practice Guidelines: Diagnosis and Management of Hepatitis C Infection in Infants, Children and Adolescents.  Journal of Pediatric Gastroenterology & Nutrition 2012 Jun;54(6):838-55.  PMID 22487950.

Leung, DH, Ahamba, DC, Pillai, LN, Khan, MF, Smith, EO, Mahoney, DH.    Unrecognized hepatitis B in pre-screened children with hematologic and oncologic conditions. Pediatric Blood & Cancer 2014 May;61(5):865-8. PMID 24249385.

Khaderi, SA, Shepherd, RW, Goss, JA, Leung, DH.  Hepatitis C in the Pediatric Population: Transmission, Natural History, Treatment and Liver Transplantation.  World Journal of Gastroenterology 2014. Aug 28;20(32):11281-11286. PMID 25170212.

Leung, DH, Ton-That, M, Economides, E, Healy, CM.  High prevalence of Hepatitis B non-immunity in vaccinated pediatric liver transplant recipients.  American Journal of Transplantation  2015 Feb;15(2):535-40. PMID 25611886.

Xue, M, Glenn, JS, and Leung, DH. Invited Review: Hepatitis D (HDV) in children. Journal of Pediatric Gastroenterology & Nutrition 2015 May 20. PMID 25988557.

Leung, DH,  Ye, Wen, Molleston, JP, Weymann, A, Ling, S, Paranjape, S, Romero, R, Schwarzenberg, S, Palermo, E, Muray, K, Marshall, B, Doo, E, Seigel, M, Krishnamurthy, R, Harned, R, Karmazyn, B, Magee, J, Narkewicz, M.  Baseline ultrasound and clinical correlates in children with Cystic Fibrosis (CF).  Journal of Pediatrics 2015 Oct;167(4):862-868. PMID 26254836.

Leung, DH, Minard, C, Guffey, D, Ramm, LE, Lewindon, P, Clouston, A, Shepherd R, Ramm, GA.  Aspartate Aminotransferase to Platelet Ratio and Fibrosis-4 as Biomarkers in Biopsy Validated Pediatric Cystic Fibrosis Liver Disease.  Hepatology 2015 Nov;62(5):1576-83.  PMID: 26223427 (BCM).

Shneider B, de Ville de Goyet J, Leung D, Srivastava A, Ling S, Duche M, McKiernan P, Superina R, Squires R, Sarin S, de Franchis R, Mazariegos G.  Primary prophylaxis of variceal bleeding in children and the role of the mesorex bypass ¬ Summary of the Baveno VI pediatric satellite symposium. Hepatology 2016. Apr;63(4):1368-80. PMID: 26358549.

Leung, DH, Narang, A, Hiremath, G, Goss, JA, Shepherd, RW.  A 10-year UNOS review of mortality and risk factors in young children awaiting liver transplantation.  Liver Transplantation  2016 Nov;22(11):1584-1592. PMID: 27541809.

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https://www.ncbi.nlm.nih.gov/sites/myncbi/daniel.leung.2/bibliography/47... descending