Texas Medical Center
1102 Bates StreetSuite 1240.08
Houston, TX 77030
Alison A. Bertuch, MD, PhD
Dr. Alison Bertuch is Director of the Bone Marrow Failure Program at Texas Children's Cancer and Hematology Center. Her clinical interests include oncology, osteosarcoma, and bone marrow failure disorders.
- Basic mechanisms of telomere maintenance, structure, and function and DNA repair in the yeast model organism and human cells
- Molecular genetics of dyskeratosis congenita and other inherited bone marrow failure syndromes
- Department of Molecular and Human Genetics, Baylor College of Medicine
- Graduate Program in Molecular and Human Genetics, Baylor College of Medicine
Dr. Alison Bertuch's research is aimed at understanding the mechanisms of telomere maintenance, structure and function. Her research uses yeast as a model system for the rapid identification and investigation of the genes that govern telomere homeostasis. Of particular interest is set of proteins previously shown to be crucial for the rejoining of DNA breaks that paradoxically also function at telomeres. In addition, Dr. Bertuch's laboratory studies the role of telomere dysfunction in the development of bone marrow failure in children. A long term goal is to exploit the knowledge gained from these studies to aid in the treatment of not only bone marrow failure, but also cancer.
She is chair of the Molecular Genetics B (MGB) Study Section of the National Institutes of Health Center for Scientific Review. Applications reviewed by the MGB study section involve molecular mechanisms of genome replication, maintenance and gene expression.
Research Interests Telomere structure and function Telomere dysfunction in the development of bone marrow failure in children
2021 Teaching and Mentorship Award, Department of Human Genetics, Baylor College of Medicine
2018 Women of Excellence Honoree, Baylor College of Medicine
2014 Elected, American Society for Clinical Investigation
2012 Research Mentorship Award, Department of Pediatrics, Baylor College of Medicine
2012 Elected, Society for Pediatric Research
2005 Faculty Education Award, Texas Children’s Cancer Center and Hematology Service
2002 Forbeck Scholar Award, William Guy Forbeck Research Foundation
1996 Ralph D. Feigin Fellowship
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