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Location

Texas Medical Center

Specialty
Cancer, Blood Disorders
Phone: 832-824-4579
Fax: 832-825-4651
Email

abertuch@texaschildrens.org

Address

1102 Bates StreetSuite 1240.08
Suite 1240.08
Houston, TX 77030

Research Laboratory

Research Area

Alison A. Bertuch, MD, PhD

Assistant Dean for Curriculum, Graduate School of Biomedical Sciences, Baylor College of Medicine
Director, Bone Marrow Failure Program
Professor, Department of Pediatrics, Section of Hematology/Oncology, Baylor College of Medicine (primary appointment)
Professor, Molecular and Human Genetics, Baylor College of Medicine
Professor, Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine

Education

School Education Degree Year
Baylor College of Medicine post-doctoral fellow Research Training 2003
Baylor College of Medicine fellowship Pediatric Hematology Oncology 1996
Baylor College of Medicine residency Pediatrics 1994
Baylor College of Medicine internship Pediatrics 1993
University of Rochester School of Medicine & Dentistry medical school Doctor of Medicine 1993
University of Rochester School of Medicine & Dentistry PhD Doctor of Philosophy, Biology 1993
Massachusetts Institute Of Technology bachelors Bachelor of Science, Biology 1985

About

Dr. Alison Bertuch is Director of the Bone Marrow Failure Program at Texas Children's Cancer and Hematology Center. Her clinical interests include oncology, osteosarcoma, and bone marrow failure disorders.

Professional Interests

  • Basic mechanisms of telomere maintenance, structure, and function and DNA repair in the yeast model organism and human cells
  • Molecular genetics of dyskeratosis congenita and other inherited bone marrow failure syndromes

Related Links

Learn more about Alison Bertuch, MD, PhD on BCM.edu

Organization

Organization Name Role
American Society of Clinical Investigation (ASCI) Member
American Society of Hematology (ASH) Member

Research Statement

Dr. Alison Bertuch's research is aimed at understanding the mechanisms of telomere maintenance, structure and function. Her research uses yeast as a model system for the rapid identification and investigation of the genes that govern telomere homeostasis. Of particular interest is set of proteins previously shown to be crucial for the rejoining of DNA breaks that paradoxically also function at telomeres. In addition, Dr. Bertuch's laboratory studies the role of telomere dysfunction in the development of bone marrow failure in children. A long term goal is to exploit the knowledge gained from these studies to aid in the treatment of not only bone marrow failure, but also cancer.

She is chair of the Molecular Genetics B (MGB) Study Section of the National Institutes of Health Center for Scientific Review. Applications reviewed by the MGB study section involve molecular mechanisms of genome replication, maintenance and gene expression.

Research Interests Telomere structure and function Telomere dysfunction in the development of bone marrow failure in children

Awards

2021   Teaching and Mentorship Award, Department of Human Genetics, Baylor College of Medicine

2018    Women of Excellence Honoree, Baylor College of Medicine

2014    Elected, American Society for Clinical Investigation

2012    Research Mentorship Award, Department of Pediatrics, Baylor College of Medicine

2012    Elected, Society for Pediatric Research

2005    Faculty Education Award, Texas Children’s Cancer Center and Hematology Service

2002    Forbeck Scholar Award, William Guy Forbeck Research Foundation

1996    Ralph D. Feigin Fellowship                 

Board Certification

American Board of Pediatrics, American Board of Pediatrics-Hematology/Oncology

Language

English

* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.