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Texas Medical Center
Specialty
Cancer, Blood Disorders
Phone: 832-824-4579
Fax: 832-825-4651
Email
abertuch@texaschildrens.org
Address
1102 Bates Ave., Ste. 1240.08
Houston, TX 77030
Research Laboratory
Research Area
Alison A. Bertuch, MD, PhD
Director, Bone Marrow Failure Program
Professor, Department of Pediatrics, Section of Hematology/Oncology, Baylor College of Medicine (primary appointment)
Professor, Molecular and Human Genetics, Baylor College of Medicine
Professor, Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine
Education
| School | Education | Degree | Year |
|---|---|---|---|
| Baylor College of Medicine | Post-doctoral Fellow | Research Training | 2003 |
| Baylor College of Medicine | Fellowship | Pediatric Hematology Oncology | 1996 |
| Baylor College of Medicine | Residency | Pediatrics | 1994 |
| Baylor College of Medicine | Internship | Pediatrics | 1993 |
| University of Rochester School of Medicine & Dentistry | Medical School | Doctor of Medicine | 1993 |
| University of Rochester School of Medicine & Dentistry | PhD | Doctor of Philosophy, Biology | 1993 |
| Massachusetts Institute Of Technology | Bachelors | Bachelor of Science, Biology | 1985 |
About
Dr. Alison Bertuch is Director of the Bone Marrow Failure Program at Texas Children's Cancer and Hematology Center. Her clinical interests include oncology, osteosarcoma, and bone marrow failure disorders.
Professional Interests
- Basic mechanisms of telomere maintenance, structure, and function and DNA repair in the yeast model organism and human cells
- Molecular genetics of dyskeratosis congenita and other inherited bone marrow failure syndromes
Related Links
Organizations
| Organization Name | Role |
|---|---|
| American Society of Clinical Investigation (ASCI) | Member |
| American Society of Hematology (ASH) | Member |
Research Statement
Dr. Alison Bertuch's research is aimed at understanding the mechanisms of telomere maintenance, structure and function. Her research uses yeast as a model system for the rapid identification and investigation of the genes that govern telomere homeostasis. Of particular interest is set of proteins previously shown to be crucial for the rejoining of DNA breaks that paradoxically also function at telomeres. In addition, Dr. Bertuch's laboratory studies the role of telomere dysfunction in the development of bone marrow failure in children. A long term goal is to exploit the knowledge gained from these studies to aid in the treatment of not only bone marrow failure, but also cancer.
She is chair of the Molecular Genetics B (MGB) Study Section of the National Institutes of Health Center for Scientific Review. Applications reviewed by the MGB study section involve molecular mechanisms of genome replication, maintenance and gene expression.
Research Interests
Telomere structure and function
Telomere dysfunction in the development of bone marrow failure in children
Selected Publications
Awards & Honors
2021 Teaching and Mentorship Award, Department of Human Genetics, Baylor College of Medicine\
2018 Women of Excellence Honoree, Baylor College of Medicine
2014 Elected, American Society for Clinical Investigation (ASCI)
2012 Research Mentorship Award, Department of Pediatrics, Baylor College of Medicine
2012 Elected, Society for Pediatric Research
2005 Faculty Education Award, Texas Children’s Cancer Center and Hematology Service
2002 Forbeck Scholar Award, William Guy Forbeck Research Foundation
1996 Ralph D. Feigin Fellowship
Board Certification
American Board of Pediatrics, American Board of Pediatrics-Hematology/Oncology
Language
English
* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.