Alison A. Bertuch, MD, PhD


  • Texas Medical Center


Blood Disorders

Phone: 832-824-4579
Fax: 832-825-4651

Contact Information

1102 Bates Street
Suite 1240.08
Houston, TX 77030
United States
Texas US

Research Laboratory

Research Area

  • Bone marrow failure

Assistant Dean for Curriculum, Graduate School of Biomedical Sciences, Baylor College of Medicine
Director, Bone Marrow Failure Program
Professor, Department of Pediatrics, Section of Hematology/Oncology, Baylor College of Medicine (primary appointment)
Professor, Molecular and Human Genetics, Baylor College of Medicine
Professor, Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine


School Education Degree Year
Baylor College of Medicine post-doctoral fellow 1997
Baylor College of Medicine fellowship Pediatric Hematology Oncology 1996
Baylor College of Medicine residency Pediatrics 1994
University of Rochester School of Medicine & Dentistry medical school Doctor of Medicine 1993
University of Rochester School of Medicine & Dentistry PhD Doctor of Philosophy 1993
Baylor College of Medicine internship Pediatrics 1993
Massachusetts Institute Of Technology bachelors Bachelor of Science 1985


Dr. Alison Bertuch is Director of the Bone Marrow Failure Program at Texas Children's Cancer and Hematology Centers. Her clinical interests include oncology, osteosarcoma, and bone marrow failure disorders.

Board Certifications

  • American Board of Pediatrics
  • American Board of Pediatrics-Hematology/Oncology

Professional Interests

  • Basic mechanisms of telomere maintenance, structure, and function and DNA repair in the yeast model organism and human cells
  • Molecular genetics of dyskeratosis congenita and other inherited bone marrow failure syndromes

Related Links

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Organization Name Role
American Society of Clinical Investigation (ASCI) Member
American Society of Hematology (ASH) Member

Research Statement

Dr. Alison Bertuch's research is aimed at understanding the mechanisms of telomere maintenance, structure and function. Her research uses yeast as a model system for the rapid identification and investigation of the genes that govern telomere homeostasis. Of particular interest is set of proteins previously shown to be crucial for the rejoining of DNA breaks that paradoxically also function at telomeres. In addition, Dr. Bertuch's laboratory studies the role of telomere dysfunction in the development of bone marrow failure in children. A long term goal is to exploit the knowledge gained from these studies to aid in the treatment of not only bone marrow failure, but also cancer.

She is chair of the Molecular Genetics B (MGB) Study Section of the National Institutes of Health Center for Scientific Review. Applications reviewed by the MGB study section involve molecular mechanisms of genome replication, maintenance and gene expression.

Research Interests
Telomere structure and function
Telomere dysfunction in the development of bone marrow failure in children