Updates

Areas of Research Neurology

Texas Children's Hospital's neurologists are faculty in the section of Pediatric Neurology and Developmental Neuroscience at Baylor College of Medicine, our academic partner. Our department has some of the world’s finest scientists and physicians who are actively investigating childhood neurological diseases with the goal of improving the standard-of-care for our patients by finding new treatments for devastating neurological conditions that are currently incurable. The research studies range the entire gamut from conducting basic research in animal models to find disease mechanism to using that knowledge to find new and improved treatments to undertaking clinical trials of new drugs and interventions. 

PediDOSE Study

Emergency medicine study designed to evaluate if a standardized method for paramedics to administer seizure medication leads to timely delivery of the right dose.

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Clinical Research

Blue Bird Circle Clinical Research Center

Physicians in the Blue Bird Circle Clinical Research Center are conducting several clinical research studies to develop new treatments for patients with neurological disorders. These include studies for autism, brachial plexus birth palsy, genetic brain malformations, epilepsy, fainting (syncope), multiple sclerosis, Duchenne’s muscular dystrophy, Rett syndrome, sleep disorders and stroke. For more information about ongoing clinical studies, please call 832-822-1253.

Texas Children's Blue Bird Circle Rett Center

The Blue Bird Circle Rett Center is one of the few centers in the US that specializes in the diagnosis and care of girls and women with Rett syndrome, a rare developmental disorder most often found in girls. The Rett Center includes a multidisciplinary team of physicians and researchers who investigate the causes of Rett syndrome and work to better diagnose and treat this disorder through the clinic at Texas Children’s and laboratories at Baylor College of Medicine.

Intellectual and Developmental Disabilities Research Center

The Intellectual and Developmental Disabilities Research Center at Baylor College of Medicine sponsors research into numerous human diseases that cause intellectual and developmental disabilities. The goals are to identify as many causes of these disorders as possible in order to prevent them, and to provide therapies that improve the quality of life of affected individuals and their families.

Basic Research

Baylor Pediatric Neurology and Developmental Neuroscience supports basic science research into the underlying causes of childhood neurological disorders. These research activities are being conducted at -

The Jan and Dan Duncan Neurological Research Institute

The Jan and Dan Duncan Neurological Research Institute (NRI) is accelerating the study and treatment of pediatric neurological disorders, such as:

  • Angelman syndrome
  • Autism
  • Cerebral palsy
  • Down syndrome
  • Epilepsy
  • Language disorders
  • Intellectual disability
  • Rett syndrome

The NRI will allow basic science and clinical research scientists to leverage emerging technologies and invent new ones. Researchers, clinicians and educators will work together in close proximity – literally and figuratively – speeding the adoption of new therapies to treat and better understand these devastating neurological conditions.

The Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories

Research being conducted at the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories seeks to better understand the biological origins of childhood epilepsy, related learning disabilities and other neurological disorders and to develop new therapies and treatments. The impact of seizures upon learning and memory formation is another area of intense research. These efforts focus on finding new treatments and cures for these debilitating conditions. Studies of early-onset epilepsy in animal models examine molecular abnormalities that lead to seizures in early life and subsequent disorders of brain development. Neuronal migration abnormalities commonly associated with intractable epilepsy are also investigated. The impact of seizures upon learning and formation of memory is also a focus of intense research.