Neuroradiology Research Group

Neuroimaging Research

The neuroimaging research mission is to improve the ability to diagnose pediatric neurologic diseases and to advance our understanding of how diseases affect the brain. We also hope to use neuroimaging to track measurable indicators that predict neurodevelopment, cognition and behavior in children.

Physicians and neuropsychologists use neuroimaging to diagnose and treat brain injuries and disorders. Neuroimaging includes various types of brain scans, including images of the anatomical structure such as CT scans and MRIs. It also includes functional and metabolic imaging of how the brain responds to tasks or stimuli, measuring blood flow in the brain and brain metabolism.

TCH neuroradiology uses neuroimaging to diagnose and treat disorders of the brain, spine, neck and central and peripheral nervous system in children. We specialize in non-invasive imaging technology, which allows us to study whole-brain maps of structural and functional brain connections.

Our world-renowned team of experts bring decades of clinical and research leadership in the diagnostic imaging of neurologic diseases, including brain tumors, brain malformations, spine disease, stroke and other vascular disorders.


Conditions We Treat Using Neuroimaging

  • Traumatic brain injury
  • Pediatric stroke
  • Congenital malformations of brain and spine
  • Epilepsy
  • Brain tumors
  • Brachial plexus injury

Scans/Imaging

  • Connectivity and tractography analysis is used in pre-surgical 3D white matter fiber visualization and helps us understand specific outcomes a brain lesion has on neural network.
  • Magnetic Resonance Imaging (MRI) allows us to assess the structure and function of the central nervous system.
  • Metabolic imaging, such as positron emission tomography (PET) scans, show us how organs and tissues are working.
  • Structural, metabolic and functional imaging allow us to use multimodality techniques to merge images, whether the images were taken at different times then fused together or taken at the same time.
  • Diffusion tensor imaging (DTI) of the brachial plexus and spinal cord allow us to better evaluate pediatric injuries.
  • Magnetic resonance spectroscopy (MRS) is modality of metabolic imaging that identifies metabolites. For example, when looking at a tumor, this imaging helps differentiate low and high-grade lesions. These scans also detect tissue changes in stroke and epilepsy patients.
  • Magnetic resonance (MR) perfusion is a technique where a contrast agent is used to measure cerebral blood volume, cerebral blood flow and mean transit time. This can add important information about potential salvageable brain tissue in stroke patients and help differentiate low and high-grade tumors.
  • Arterial spin labeling (ASL) perfusion is a non-invasive MRI technique used to measure the brain perfusion at the tissue level.
  • Functional magnetic resonance imaging (fMRI) measures blood oxygenation changes that occur in the brain. These images could be used to determine which parts of the brain are handling critical functions or to evaluate the effects of a stroke or disease.  Additionally, this technique is crucial for pre-surgical planning in patients with epilepsy or brain tumor.

Equipment and Software

  • State of the art 3 tesla scanners produce high-quality DTI and resting stat fMRI.
  • Our high-performance neuroimaging research lab includes advanced hardware and post-processing software for connectome analysis.