Thomas D. Horvath, PhD
Instructor, Pathology & Immunology, Baylor College of Medicine
Phone:
832-824-0904
Languages: English
Departments:
Get to know Thomas D. Horvath, PhD
Dr Horvath’s efforts are keenly focused on the development of bioanalytical methods to measure endogenous and exogenous small-molecules and proteins from an assortment of biological fluids and tissue extracts. As a member of the TCH-Microbiome Center, he applies LC-MS/MS-based methods to examine how specific microbial-derived metabolites or proteins can benefit, impede, or be diagnostic of the human health condition. His interest is in developing targeted metabolomics methods has resulted in a number of publications that report how specific microbes can influence intestinal biology and modulate the mammalian gut-brain-axis.
Education
| School | Education | Degree | Year |
|---|---|---|---|
| University of Michigan | PhD | Doctor of Philosophy | 2008 |
| University of Michigan | Masters | Master of Science | 2002 |
| Eastern Michigan University | Bachelors | Bachelor of Science | 2000 |
| Ivy Tech State College | Associates | Associates | 1996 |
Organizations
| Organization Name | Role |
|---|---|
| American Association for the Advancement of Science (AAAS) | Member |
| American Chemical Society (ACS) | Member |
| American Society for Mass Spectrometry (ASMS) | Member; Co-Chair of the Metabolomics Interest Group |
| Cell Press, STAR Protocols | Associate Academic Editor |
| Metabolomics Association of North America (MANA) | Member |
* Texas Children’s Hospital physicians’ licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician’s office and were not verified by Texas Children’s Hospital.
Horvath TD*, Ihekweazu FD*, Haidacher SJ, Ruan W, Engevik KA, Fultz R, Hoch KM, Luna RA, Oezguen N, Spinler JK, Haag AM, Versalovic J, Engevik MA. Bacteroides ovatus colonization influences the abundance of intestinal neurotransmitters. iScience, 2022, 25:104158.
Fultz R, Ticer T, Ihekweazu FD, Horvath TD, Haidacher SJ, Hoch KM, Bajaj M, Spinler JK, Haag AM, Buffington SA, Engevik MA. Unraveling the metabolic requirements of the gut commensal Bacteroides ovatus. Frontiers in Microbiology, 2021, 12:745469.
Luck B*, Horvath TD*, Engevik KA, Ruan W, Haidacher SJ, Hoch KM, Oezguen N, Spinler JK, Haag AM, Versalovic J, Engevik MA. Neurotransmitter profiles are altered in the gut and brain of mice mono-associated with Bifidobacterium dentium. Biomolecules, 2021, 11:1091.
Engevik MA, Herrmann B, Ruan W, Engevik AC, Engevik KA, Ihekweazu FD, Shi Z, Luck B, Chang-Graham AL, Esparza M, Venable S, Horvath TD, Haidacher SJ, Hoch KM, Haag AM, Schady DA, Hyser JM, Spinler JK, Versalovic J. Bifidobacterium dentium-derived y-glutamylcysteine suppresses ER-mediated goblet cell stress and reduces TNBS-driven colonic inflammation. Gut Microbes, 2021, 13(1):1-21. MyNCBI Link: https://www.ncbi.nlm.nih.gov/myncbi/1HWR7-aFsd7cyq/bibliography/public/