Dr. Meenakshi Hegde is a pediatric oncologist engaged in translational research on immunotherapy to improve patient outcomes in high-risk cancer. Her research was the first to demonstrate that a highly heterogeneous landscape of antigen expression in glioblastoma and other solid tumors benefitted from simultaneous targeting of these antigens using a novel bispecific CAR T-cell (TanCAR).
Her current efforts focus on the tumor complex rather than the tumor cell to develop effective T-cell based platform resistant to the inhibitory pathways within the tumor environment and translation of newly developed cellular therapies from the laboratory to clinic through well-designed clinical trials to shape standard of care practices in the field of high-risk cancer therapy. Her clinical interests span adoptive cellular therapy and bone marrow transplant.
Dr. Hegde is a member of the Brain Tumor Research Program at Texas Children's Cancer Center, the Center for Cell and Gene Therapy, and the Bone Marrow / Stem Cell Transplant Program.
She is a board certified physician-specialist in pediatric hematology/oncology and a member of the American Board of Pediatrics.
American Board of Pediatrics
American Board of Pediatrics - Pediatric Hematology/Oncology