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Texas Medical Center
Specialty
Gastroenterology, Hepatology and Nutrition
Phone: 832-822-3131
Address
6701 Fannin Street
Suite 1100
Houston, TX 77030
Geoffrey A. Preidis, MD, PhD
Director, Neonatal Gastroenterology, Hepatology & Nutrition Consultation Service
Assistant Professor, Pediatric Gastroenterology, Baylor College of Medicine (BCM)
Associate Director, Medical Scientist Training Program (MD/PhD), BCM
Faculty, Development, Disease Models & Therapeutics Graduate Program, BCM
Faculty, Immunology & Microbiology Graduate Program, BCM
Faculty, Clinical Scientist Training Program, BCM
Education
| School | Education | Degree | Year |
|---|---|---|---|
| Baylor College of Medicine | Fellowship | Pediatric Gastroenterology, Hepatology & Nutrition | 2018 |
| Baylor College of Medicine | Internship/Residency | Pediatrics | 2014 |
| Baylor College of Medicine | Medical School | Doctor of Medicine | 2012 |
| Baylor College of Medicine | PhD | Translational Biology and Molecular Medicine | 2011 |
| Harvard University | Bachelor of Arts (AB) in Physics (cum laude) | 2003 |
About
Dr. Preidis’s goal is to provide the highest quality of compassionate patient care by leveraging the latest advances in gastroenterology, hepatology, nutrition and microbiome research.
Clinical Interests: Neonatal gastroenterology, hepatology and nutrition, pediatric liver disease, transplant hepatology, neurogastroenterology and motility, general pediatric gastroenterology
Research Interests:
Dr. Preidis’ NIH-funded laboratory aims to define mechanisms through which early life malnutrition alters metabolism and to determine how malnutrition impairs intestinal and liver function. Undernutrition causes acute medical problems, but also long-term health problems that may result from permanent epigenetic changes that alter transcription or via changes in the gut microbiome. Current studies focus on how malnutrition impairs bile acid synthesis, causes fatty liver disease, slows gastrointestinal motility, and alters host-microbiome interactions to impact child growth. This work is relevant to those suffering from nutritional deficiencies caused by a wide range of medical and psychosocial factors, including preterm and underweight newborns in the neonatal intensive care unit, adolescents with anorexia nervosa and children with severe acute malnutrition.
Organizations
| Organization Name | Role |
|---|---|
| American Academy of Pediatrics | Fellow |
| American Association for the Study of Liver Diseases | Member |
| American Gastroenterological Association | Member |
| American Neurogastroenterology and Motility Society | Member |
| American Physiological Society | Member |
| American Society for Nutrition | Member |
| Frontiers in Immunology | Associate Editor |
| Frontiers in Microbiology | Associate Editor |
| Gut Microbes | Associate Editor |
| Human Capital and Economic Opportunity Working Group | Member |
| Society for Pediatric Research | Member |
Selected Publications
Shane AL, Preidis GA. Probiotics in the neonatal intensive care unit – a framework for optimizing product standards. JAMA Pediatrics 2023; 177(9):879-880.
Lynch LE, Hair AB, Soni KG, Yang H, Gollins LA, Narvaez-Rivas M, Setchell KDR, Preidis GA. Cholestasis impairs gut microbiota development and bile salt hydrolase activity in preterm neonates. Gut Microbes 2023;15:2183690.
Neves LL, Hair AB, Preidis GA. A systematic review of associations between gut microbiota composition and growth failure in preterm neonates. Gut Microbes 2023;15:2190301.
Preidis GA. Rational probiotic strain selection to prevent necrotizing enterocolitis. J Pediatr Gastroenterol Nutr 2022;75:387-388.
Suh JH, Kim KH, Conner ME, Moore DD, Preidis GA. Hepatic PPARα is destabilized by SIRT1 deacetylase in undernourished male mice. Front Nutr 2022;9:831879.
Soni KG, Dike PN, Suh JH, Halder T, Edwards PT, Foong JPP, Conner ME, Preidis GA. Early‐life malnutrition causes gastrointestinal dysmotility that is sexually dimorphic. Neurogastroenterol Motil 2020;32:e13936.
Preidis GA, Weizman AV, Kashyap PC, Morgan RL. AGA technical review on the role of probiotics in the management of gastrointestinal disorders. Gastroenterology 2020;159:708-738.
Awards & Honors
The Metabolic Basis for Impaired Bile Acid Synthesis in Malnutrition (R01 DK133301), National Institute of Diabetes and Digestive and Kidney Diseases, 2022 – 2027.
Young Investigator Award, Department of Pediatrics, Baylor College of Medicine, 2022.
Society for Pediatric Research, Inductee, 2022.
Impaired bile acid synthesis due to CYP7A1 and CYP7B1 suppression in malnutrition (R03 DK129495), National Institute of Diabetes and Digestive and Kidney Diseases, 2021 – 2023.
Mentored Clinical Scientist Research Career Development Award (K08), National Institute of Diabetes and Digestive and Kidney Diseases, 2017 – 2022.
Chao Physician-Scientist Award, Ting Tsung and Wei Fong Chao Foundation, 2017.
American Gastroenterological Association (AGA)-Rome Foundation Functional GI and Motility Pilot Award, 2017 – 2018.
Basic Research Award for Fellows, Society for Pediatric Research, presented at Pediatric Academic Societies 2017 Annual Meeting, San Francisco, CA, 2017.
Research Grant, American Neurogastroenterology and Motility Society (ANMS), 2017.
Pilot/Feasibility Award, The Texas Medical Center Digestive Diseases Center, 2016 – 2017.
North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) Foundation Young Investigator Award / Nestle Nutrition Research Award, 2015 – 2017.
Early Career Award, Thrasher Research Fund, 2013 - 2014.
Young Investigator Grant for Probiotics Research, Global Probiotics Council, 2013 – 2014.
* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.