Edward John Hickey, MD


  • Texas Medical Center


Congenital Heart Surgery

Phone: 832-826-2030

Contact Information

6651 Main Street
Legacy Tower, 21st Floor
Houston, TX 77030
United States

Surgical Director, Adult Congenital Heart Disease Program

Texas Children's Hospital

Associate Surgeon, Congenital Heart Surgery, Texas Children’s Hospital

Associate Professor of Surgery, Division of Congenital Heart Surgery, Baylor College of Medicine


School Education Degree Year
The Hospital for Sick Children fellowship Pediatric Cardiac Surgery 2012
Cardiac Surgery University of Toronto residency Cardiac Surgery 2010
Royal College of Physicians and Surgeons of Canada other FRCSC, Cardiac Surgery 2010
University of Southampton other Doctoral Research Thesis (DM) 2007
University of Southampton Medical School medical school Doctor of Medicine 1999


My goal is for all children born with congenital heart disease to enjoy healthy and active lives, far beyond their childhood years. Although I operate on the full age and diagnostic spectrum, a particular focus of mine is to expand and develop our Adult Congenital Heart Disease (ACHD) practice. Adults have historically suffered greatly limited access to congenital heart disease expertise; a disparity that we are striving to correct at Texas Children’s Hospital.

I am excited to partner with Dr Peter Ermis, Medical Director of Adult Congenital Heart Disease, to lead the expansion of Texas Children’s Hospital Adult Congenital Heart Disease Program. In November 2020 we will be opening the Legacy Tower 24th floor: a 27,000 ft2 dedicated ACHD center, complete with 16 intensive care beds, diagnostics unit and rehabilitation/gym facility. This will be the most advanced ACHD program in the southern US and the highest concentration of specialist ACHD expertise in the region. For congenital heart disease, Texas Children’s Hospital is your home for life. All ages. All diagnoses. All complexity.

I previously oversaw the largest Canadian ACHD surgical program (Toronto 2012 -2019) including establishing the busiest ACHD transplant practice in Canada.

Clinical Interests:

· Neonatal, infant and pediatric congenital heart surgery

· Surgery for Adult congenital heart disease

· Heart transplantation and mechanical support

· Extra-corporeal membrane oxygenation (ECMO)

· Adult congenital heart transplantation and advanced therapies

Research Interests:

· Parametric non-linear time-related outcomes analyses

· Natural history studies and prediction modelling using large congenital heart disease research datasets

· Threat and error modelling and understanding error propagation

· “Flight plan” clinical review for quality improvement

I was the 2006 – 2008 Kirklin-Ashburn fellow with the Congenital Heart Surgeons’ Society and thereby became trained in the art and science of non-linear modelling under the tutelage of Dr Eugene Blackstone. These techniques have provided the foundation for the clinical outcomes analyses that have formed the bulk of my research activity.

In recent years, I introduced the concept of “flight plan” review of patient journeys and translated threat and error modelling from the aviation industry to congenital heart surgery. This has proved to be an effective risk-containment and quality improvement tool that has subsequently been implemented in many other centers. 


Organization Name Role
Royal College of Physicians and Surgeons of Canada Cardiac Surgery Examiner and Examination Board Executive Committee Member (2016 - Present)

Selected Publications

Hickey EJ, Halvorsen F, Laussen PC, Hirst G, Schwartz S, Van Arsdell GS. Chasing the 6-sigma: drawing lessons from the cockpit culture. Journal of Thoracic and Cardiovascular Surgery 2018;155:690-6.

Meza, Hickey, Blackstone, Jaquiss, Anderson, Williams, Cai, Van Arsdell, Karamlou, McCrindle. The optimal timing of stage-2 palliation for hypoplastic left heart syndrome: an analysis of the Pediatric Heart Network Single Ventricle Reconstruction Trial Public Dataset. Circulation 2017 Oct 31;136(18):1737-1748.

Hickey EJ, Nosikova Y, Pham-Hung E, Gritti M, Schwartz S, Caldarone CA, Redington A, Van Arsdell GS. National Aeronautics and Space Administration “threat and error” model applied to pediatric cardiac surgery: error cycles precede ∼85% of patient deaths. Journal of Thoracic and Cardiovascular Surgery 2015 Feb;149(2):496-505.

Hickey EJ, Pham-Hung E, Nosikova Y, Halvorsen F, Gritti M, Schwartz S, Caldarone CA, Van Arsdell GS. National Aeronautics and Space Administration model of “threat and error” in pediatric cardiac surgery: patterns of error chains. Annals of Thoracic Surgery 2017;103:1300-7.

Wilder, Van Arsdell, Benson, Pham-Hung, Gritti, Page, Caldarone, Hickey. Young infants with severe tetralogy of Fallot: early primary surgery versus transcatheter palliation. Journal of Thoracic and Cardiovascular Surgery 2017 Nov;154(5): 1692-1700.

Wilder, McCrindle, Hickey, Ziemer, Tchervenkov, Jacobs, Gruber, Blackstone, Williams, DeCampli, Caldarone, Pizarro. Is a hybrid a lower-risk alternative to stage-1 Norwood operation? Journal of Thoracic and Cardiovascular Surgery 2017 Jan;153(1):163-172.

Wilder, McCrindle, Phillips, Blackstone, Rajeswaran, Williams, DeCampli, Jacobs, Jacobs, Karamlou, Kirshbolm, Lofland, Ziemer, Hickey. Survival and right ventricular performance for matched children after stage-1 Norwood with Blalock-Taussig shunt versus Norwood with right ventricle to pulmonary artery conduit. Journal of Thoracic and Cardiovascular Surgery 2015 Dec;150(6):1440-50.