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Department
LocationCancer and Hematology Center
Sickle Cell and Thalassemia Program
William T. Shearer Center for Human Immunobiology
Texas Medical Center
Specialty
Cancer and Hematology
Email
danitza.nebor@bcm.edu
Address
1102 Bates Ave., Ste. 1570
Houston, TX 77030
Research Area
Danitza M. Nébor, PhD
Instructor, Department of Pediatrics, Section of Hematology/Oncology, Baylor College of Medicine
Education
| School | Education | Degree | Year |
|---|---|---|---|
| The Jackson Laboratory | Post-doctoral Fellow | 2018 | |
| University of French West Indies / University Paris VII National institute of health and medical research (Inserm) | PhD | Doctor of Philosophy | 2010 |
| University of Paris VII | Postgraduate Education | 2006 | |
| University of Poitiers | Masters | Master of Science, Physiology, cellular and molecular biology | 2006 |
| University of Poitiers | Bachelors | Bachelor of Science, Cellular biology and physiology | 2004 |
About
Dr. Danitza Nébor is an instructor in the Department of Pediatrics at Baylor College of Medicine with a longstanding interest in the pathophysiology of sickle cell disease (SCD). Her mission is to develop new therapeutic strategies that will be accessible and affordable to every patient with SCD.
Dr. Nébor earned her PhD in France where she evaluated the role of microparticles, genetic modifiers and the autonomic nervous system on patients' inflammatory state, vaso-occlusion and chronic complications. She then moved to the USA to join the Jackson Laboratory where she received a strong formal training and became an expert in mouse handling, surgeries, biomethods and colony management.
Dr. Nébor's current research focuses on the identification of new treatments to improve SCD outcomes and the generation of new mouse models that will be important resources for the scientific community.
Research interests
Sickle cell disease
hemoglobinopathies
Organizations
| Organization Name | Role |
|---|---|
| American Society of Hematology (ASH) | Member |
| Society for Pediatric Research (SPR) | Member |
Selected Publications
Kanne C*, Nebor D* (Co-first author), Pochron M, Oksenberg D, Sheehan V. Rheological Impact of GBT1118 Cessation in a Sickle Mouse Model. Frontiers in Physiology, section Red Frontier in Physiology. 2021 Sep 24;12:742784 PubMed PMID: 34630162; PubMed Central PMCID: PMC8497897.
Nébor D, Graber JH, Ciciotte SL, Robledo RF, Papoin J, Hartman E, Gillinder KR, Perkins AC, Bieker JJ, Blanc L, Peters LL. Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis. Sci Rep. 2018 Aug 24;8(1):12793. Pubmed PMID: 30143664; PubMed Central PMCID: PMC6109071
Nebor D, Bowers A, Connes P, Hardy-Dessources MD, Knight-Madden J, Cumming V, Reid M, Romana M. Plasma concentration of platelet-derived microparticles is related to painful vaso-occlusive phenotype severity in sickle cell anemia. PLoS One. 2014;9(1):e87243. PubMed PMID: 24475257; PubMed Central PMCID: PMC3901744.
Nébor D, Romana M, Santiago R, Vachiery N, Picot J, Broquere C, Chaar V, Doumdo L, Odièvre MH, Benkerrou M, Elion J. Fetal hemoglobin and hydroxycarbamide moduate both plasma concentration and cellular origin of circulating microparticles in sickle cell anemia children. Haematologica. 2013 Jun;98(6):862-7. PubMed PMID: 23403312; PubMed Central PMCID: PMC3669440
Nebor D, Bowers A, Hardy-Dessources MD, Knight-Madden J, Romana M, Reid H, Barthélémy JC, Cumming V, Hue O, Elion J, Reid M, Connes P. Frequency of pain crises in sickle cell anemia and its relationship with the sympatho-vagal balance, blood viscosity and inflammation. Haematologica. 2011 Nov;96(11):1589-94. PubMed PMID: 21750084; PubMed Central PMCID: PMC3208675
Awards & Honors
| 2022 | ASH Scholar Award (Transition to assistant professor) |
| 2022 | PRomotion of FellOwS‘ PEdiatric Research (PROSPER) Diversity Awards, Society for Pediatric Research (SPR) |
| 2021 | Programs to Increase Diversity Among Individuals Engaged in Health-Related Research, NHLBI |
| 2020 | Restart Award, American Society of Hematology (ASH) |
| 2016 | Abstract Achievement Award / 58th ASH Annual Meeting |
| 2015 | Scholar Award, American Society of Hematology (ASH) |
| 2014 | Abstract Achievement Award, American Society of Hematology (ASH) 56th Annual Meeting |
| 2014 | Under-represented Minority Scholarship Award, IMGC |
| 2011 | Best PhD in science, University of the French West Indies |
| 2010 | Best Oral Communication, Red Cell and Iron Club, Marseille, France |
| 2010 | Thesis received special honors and highest distinction from jury, University of the French West Indies/ Paris VII |
| 2009 | Best Oral Presentation for Popularization, University of the French West Indies |
Language
English
* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.