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Texas Medical Center

Emergency Medicine
Phone: 832-824-5497
Fax: 832-825-5424


6621 Fannin Street
Suite A2210
Houston, TX 77030

Andrea T. Cruz, MD, MPH

Research Chief, Pediatric Emergency Medicine

Site Principal Investigator, Pediatric Emergency Care Applied Research Network (PECARN)
Director, Children’s Tuberculosis Clinic
Professor, Pediatrics - Emergency Medicine, Baylor College of Medicine


School Education Degree Year
University of Texas at Houston Masters Master of Public Health 2009
Baylor College of Medicine Fellowship Pediatric Emergency Medicine 2005
Baylor College of Medicine Fellowship Pediatric Infectious Disease 2005
Baylor College of Medicine Residency Pediatrics 2004
Baylor College of Medicine Internship Pediatrics 2002
Vanderbilt University Medical School Doctor of Medicine 2001


Dr. Cruz completed fellowships in pediatric emergency medicine and pediatric infectious diseases, as well as an MPH in epidemiology with a focus on global health at the University of Texas School of Public Health. She is research chief for pediatric emergency medicine (PEM), focusing on advancing the clinical research within PEM by fellows and faculty, as well as assisting in establishing collaborations with colleagues within and outside of the Department of Pediatrics. She is the co-site principal investigator for the Pediatric Emergency Care Applied Research Network (PECARN), a network of 18 academic tertiary care pediatric emergency departments throughout the United States. Her personal research interests include diagnosis of infectious diseases in the emergency department, optimizing the treatment of septic shock, and childhood tuberculosis.

Dr. Cruz only sees patients in the Emergency Center and in the Children's Tuberculosis Clinic at Texas Children's Hospital. Appointments in TB Clinic need to be arranged through a child's primary care provider or the health department. Parents cannot self-refer to the TB Clinic.

Clinical Interests

Infections in the emergency department 

Rapid diagnostic assays for infectious diseases 


Childhood tuberculosis 

Research Interests


Childhood tuberculosis 

Viral diagnostics 


Organization Name Role
American Pediatric Association Co-Chair, Pediatric Emergency Medicine Special Interest Group
American Pediatric Association Section of Emergency Medicine: vice-chair, Pediatric Emergency Medicine Collaborative Research Committee
Pediatrics Journal Associate Editor

Selected Publications

Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Pediatric Critical Care Medicine 2020;21(2):e52-e106. PMID 32032273.  

Snow KJ, Cruz AT, Seddon J, Ferrand AR, Chiang SS, Hughes JA, Kampmann B, Graham SM, Dodd PJ, Houben RM, Denholm JT, Sawyer SM, Kranzer K. Adolescent tuberculosis: the missing middle. Lancet Child and Adolescent Health 2020;4(1):69-79. PMID 31753806.  

Cruz AT, Starke JR. Window prophylaxis for children exposed to tuberculosis. Emerging Infectious Diseases 2019;25(3):523-528. PMID 30789136.  

Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle Jr JJD, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P. A clinical prediction rule to identify febrile infants 60 days and younger at low risk for serious bacterial infections. JAMA Pediatrics 2019;173(4):342-351. PMID 30776077.   

Cruz AT, Starke JR. Completion rate and safety of tuberculosis treatment with shorter regimens. Pediatrics 2018;141(2):e20172838. PMID 29363561.  

Cruz AT, Freedman SB, Kulik D, Okada PJ, Fleming AH, Mistry RD, Thomson JE, Schnadower D, Arms JL, Mahajan P, Garro AC, Pruitt CM, Balamuth F, Uspal NG, Aronson PL, Lyons TW, Thompson AD, Curtis SJ, Ishimine PT, Schmidt SM, Bradin SA, Grether-Jones KL, Miller AS, Louie J, Shah SS, Nigrovic LE. Frequency of herpes simplex viral infection in a multicenter emergency department study of infants ≤60-days-old undergoing evaluation for central nervous system infection. Pediatrics 2018;141(2):e20171688. PMID 29298827.  

Cruz AT, Mahajan P, Bonsu BK, Bennett JE, Levine DA, Alpern ER, Nigrovic LE, Atabaki SM, Cohen DM, van Buren J, Ramilo O, Kuppermann N for the Pediatric Emergency Care Applied Research Network (PECARN). Accuracy of blood cell counts to detect invasive bacterial infections in 0-60-day-old infants. JAMA Pediatrics 2017;171(11):e172927. PMID 28892537.  

View PubMed Publications

View VIICTR Publications

Board Certification

American Board of Pediatrics


English, Spanish

* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.