Ananth V. Annapragada, PhD
- Texas Medical Center
Vice Chief, Research
Texas Children's Hospital
Professor of Radiology, Baylor College of Medicine
|Massachusetts Institute of Technology||post-doctoral fellow||1991|
|University of Minnesota||post-doctoral fellow||1990|
|University of Michigan||PhD||Doctor of Philosophy, Chemical Engineering||1989|
Ananth Annapragada is Professor of Radiology and Director of Basic Research in the Edward B. Singleton Department of Pediatric Radiology at Texas Children's Hospital. Previously, he was the Robert Graham Professor of Entrepreneurial Biomedical Informatics and Bioengineering at the School of Biomedical Informatics at the University of Texas, Health Sciences Center at Houston. He holds additional positions at the Keck Institute, The University of Houston, Rice University and the University of Texas at Austin.
Ananth received his Ph.D. in Chemical Engineering from The University of Michigan in 1989. After postdoctoral fellowships at the University of Minnesota and MIT, he joined Abbott Laboratories as a Research Scientist in 1991. In 1996, he joined SEQUUS Pharmaceuticals, Menlo Park, CA and stayed on till it was acquired by Johnson and Johnson. In 2000, he started his first academic position at the Cleveland State University and Cleveland Clinic Foundation. In 2003, he moved to University of Texas and subsequently, joined Texas Children's Hospital in June 2011.
Dr. Annapragada's research interests are in the development of nanomaterial based solutions to medical and imaging problems. Some examples of his work in the field are the development of novel nanoparticle contrast agents for both CT and MR, “Intelligent” nanostructures for glucose responsive insulin delivery, and targeted nanostructures for imaging and therapy.
Bhavane R, Badea C, Ghaghada KB, Clark D, Vela D, Moturu A, et al. Dual-Energy Computed Tomography Imaging of Atherosclerotic Plaques in a Mouse Model Using a Liposomal-Iodine Nanoparticle Contrast Agent. Circ Cardiovasc Imaging 2013 Jan 24.
Espinosa G, Annapragada A. Cost-Effectiveness of a Novel Blood-Pool Contrast Agent in the Setting of Chest Pain Evaluation in an Emergency Department. AJR American Journal of Roentgenology 2013 Oct;201(4):710–9.
Wu J, Mu Q, Thiviyanathan V, Annapragada A, Vigneswaran N. Cancer stem cells are enriched in Fanconi anemia head and neck squamous cell carcinomas. Int J Oncol 2014 Dec;45(6):2365–72.
Starosolski Z, Villamizar CA, Rendon D, Paldino MJ, Milewicz DM, Ghaghada KB, et al. Ultra High-Resolution In vivo Computed Tomography Imaging of Mouse Cerebrovasculature Using a Long Circulating Blood Pool Contrast Agent. Sci Rep 2015;5:10178.
Annapragada A. Advances in Nanoparticle Imaging Technology for Vascular Pathologies. Annu Rev Med 2015 Jan 14;66:177–93.
Sabapathy DG, Guillerman RP, Orth RC, Zhang W, Messinger Y, Foulkes W, et al. Radiographic Screening of Infants and Young Children With Genetic Predisposition for Rare Malignancies: DICER1 Mutations and Pleuropulmonary Blastoma. AJR American Journal of Roentgenology 2015 Apr;204(4):W475–82.