Moreshwar S. Desai, MD
Department or Service
- Texas Medical Center
Associate Professor of Pediatrics, Section of Critical Care Medicine
Baylor College of Medicine
|Baylor College of Medicine||fellowship||Pediatric Critical Care||2007|
|Children's Hospital of Michigan||residency||Pediatrics||1997|
|Seth Gordhandas Sunderdas Medical College||medical school||Doctor of Medicine||1993|
Dr. Desai is interested in the molecular mechanisms of cardiac dysfunction in cirrhotic liver diseases. Along with his mentor, Dr. Saul Karpen, he has shown a new form of cardiomyopathy in infants and children with end stage cirrhotic liver disease secondary to biliary atresia and have shown that abnormal cardiac function in these infants affects post-transplant hospital and ICU length of stay. They have also reproduced key features of cardiomyopathy seen in clinical practice in novel mouse models of cholestasis and liver injury in an attempt to understand the pathophysiology and molecular mechanisms of cardiac dysfunction, termed- Cirrhotic Cardiomyopathy. Dr. Desai has successfully finished a project looking at the role of TLR4 and TLR2 in steatohepatitis with atherogenic diet.
|Society of Critical Care Medicine||Member|
Xu Z, Desai M, Philip J, Sivsubramanian N, Bowles NE, Vallejo JG. Conditional transgenic expression of TIR-domain-containing adaptor-inducing interferon-? (TRIF) in the adult mouse heart is protective in acute viral myocarditis. Basic Research in Cardiology 2011 Sept 29 (Epub ahead of print) PMID: 21956162.
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