Texas Medical Center
One Baylor PlazaAlkek Building for Biomedical Research, ABBR-500
Alkek Building for Biomedical Research, ABBR-500
Houston, TX 77030
Melissa A. Richard, PhD
Dr. Melissa Richard is a genetic epidemiologist with a focus on using integrative, modern genetic-based approaches to uncover the molecular basis of disease.
She has a particular focus on using multi-omic measures to characterize cardiometabolic traits as both a cause and consequence of health outcomes.
Her current work uses genetic epidemiologic techniques to uncover the molecular basis of disrupted metabolism in survivors of childhood cancer, as well as the influence of metabolic traits on human development.
She is also interested in understanding the altered mechanisms that contribute to the development of certain congenital anomalies, such as hypospadias.
Sung YJ, Winkler TW, de Las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I, Guo X, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Feitosa MF, Kilpeläinen TO, Richard MA, Noordam R, Aslibekyan S, et al. "A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure." Am J Hum Genet. 2018 March;102(3) Pubmed PMID: 29455858
Haight T, Bryan RN, Meirelles O, Tracy R, Fornage M, Richard M, Nasrallah I, Yaffe K, Jacobs DR Jr, Lewis C, Schreiner P, Sidney S, Davatzikos C, Launer LJ. "Associations of plasma clusterin and Alzheimer's disease-related MRI markers in adults at mid-life: The CARDIA Brain MRI sub-study." PLoS One. 2018 Pubmed PMID: 29324756
Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, Irvin MR, Marioni R, Shen J, Tsai PC, Montasser ME, Jia Y, Syme C, Salfati EL, Boerwinkle E, Guan W, Mosley TH Jr, Bressler J, Morrison AC, Liu C, Mendelson MM, Uitterlinden AG, et al. "DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation." Am J Hum Genet. 2017 December;101(6) Pubmed PMID: 29198723
Nandakumar P, Lee D, Richard MA, Tekola-Ayele F, Tayo BO, Ware E, Sung YJ, Salako B, Ogunniyi A, Gu CC, Grove ML, Fornage M, Kardia S, Rotimi C, Cooper RS, Morrison AC, Ehret G, Chakravarti A. "Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry." J Hypertens. 2017 July;35(7) Pubmed PMID: 28234671
Avery CL, Wassel CL, Richard MA, Highland HM, Bien S, Zubair N, Soliman EZ, Fornage M, Bielinski SJ, Tao R, Seyerle AA, Shah SJ, Lloyd-Jones DM, Buyske S, Rotter JI, Post WS, Rich SS, Hindorff LA, Jeff JM, Shohet RV, Sotoodehnia N, Lin DY, et al. "Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations." Heart Rhythm. 2017 April;14(4) Pubmed PMID: 27988371
Sung YJ, Winkler TW, Manning AK, Aschard H, Gudnason V, Harris TB, Smith AV, Boerwinkle E, Brown MR, Morrison AC, Fornage M, Lin LA, Richard M, Bartz TM, Psaty BM, Hayward C, Polasek O, Marten J, Rudan I, Feitosa MF, Kraja AT, Province MA, et al. "An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group." Genet Epidemiol. 2016 July;40(5) Pubmed PMID: 27230302
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