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Texas Medical Center

Phone: 832-824-1319
Fax: 832-825-1260


6701 Fannin Street
11th Floor
Houston, TX 77030

Eyal Muscal, MD, MS

Division Chief, Pediatric Rheumatology

Pawelek Endowed Chair of Pediatric Rheumatology
Co Appointment: Child Neurology and Developmental Neuroscience
Associate Professor of Pediatrics, Pediatric Rheumatology, Baylor College of Medicine


School Education Degree Year
UT Health Science at Houston Masters Master of Science in Clinical Research 2008
Baylor College of Medicine Fellowship Pediatric Rheumatology 2007
Children's Hospital-Pittsburgh Residency Pediatrics 2003
Children's Hospital-Pittsburgh Internship Pediatrics 2001
Jefferson Medical College Medical School Doctor of Medicine 2000
Brown University Bachelors Bachelor of Arts 1993


I am a pediatric rheumatologist with a Master of Science degree in clinical research. My practice focuses on patient care, fellowship education and clinical research. My interest in immunoneurology has led to a secondary appointment in the Child Neurology division at Baylor College of Medicine. 

I have received grant funding and research awards for pilot research studies. I was previously the Pediatric Rheumatology program director and led a national pediatric rheumatology-mentoring project. I have been the Pediatric Rheumatology division chief for four years. 

Clinical Interests: Neurologic manifestations of rheumatic disorders, novel and auto-inflammatory mechanisms of neuroinflammatory disease

Research Interests: neurologic manifestation of systemic autoimmune disorders and isolated neuronal immune-dysregulatory disorders (autoimmune encephalitis, NORSE, and Rasmussen’s encephalitis)


Organization Name Role
American College of Rheumatology Previous Early career Investigator Sub-committee member
AMIGO (ACR, CARRA Mentoring interest Group) Previous Co-Director
Childhood Arthritis and Rheumatology Research Alliance Voting member, co-director inflammatory brain disease workgroup
Norse Institute Medical advisory board member

Selected Publications

Alexander J. Sandweiss, Varun Kannan, Nilesh Desai, Stephen Kralik, Eyal Muscal, and Kristen Fisher. Arterial spin labeling changes parallel asymmetric perisylvian and perirolandic symptoms in 3 pediatric cases of anti-NMDAR encephalitis. Neurology: Neuroimmunology & Neuroinflammation; NEURIMMINFL/ 2022/040738 (Accepted for publication).

Vreeland A, Thienemann M, Cunningham M, Muscal E, Pittenger C, Frankovich J. Neuroinflammation in Obsessive-Compulsive Disorder: Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections, and Pediatric Acute Onset Neuropsychiatric Syndrome. Psychiatr Clin North Am. 2023 Mar;46(1):69-88. doi: 10.1016/j.psc.2022.11.004. PMID: 36740356.

Lai YC, Abou-El-Kheir G, Nguyen T, Hanerhoff M, Riviello JJ, Muscal E. Systemic inflammatory markers and EEG features of children with FIRES receiving anakinra. Ann Clin Transl Neurol. 2023 Jan 16. Epub ahead of print. PMID: 36645080.

Son MB, Berbert L, Young C et al. (Muscal E as 14th author). Post-Discharge glucocorticoid use and clinical outcomes in multisystem inflammatory syndrome in children. JAMA Open Network. 2022, 5 (11): PMID: 36367723

Wickstrom R, et al, (Muscal E one of authors from The International NORSE Consensus Group). International Consensus recommendations for management of new onset refractory status epilepticus (NORSE) including febrile infection-related epilepsy syndrome (FIRES): Summary and clinical tools. Epilepsia. Aug. 2022. Online ahead of print . PMID: 35951466

Jain PN, Acosta S, Annapragada A, Checchia PA, Moreira A, Muscal E, Sartain SE, Tejtel SKS, Vogel TP, Shekerdemian L, Rusin CG. Comparison of laboratory and hemodynamic time series data across original, alpha, and delta variants in patients with multisystem inflammatory syndrome in children. Pediatr Crit Care Med. 2022 May 04. PMID: 35507775.

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* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.