Chandrasekhar Yallampalli, DVM, PhD
Reproductive Endocrinologist, Texas Children’s Pavilion for Women
Professor, Departments of Obstetrics and Gynecology and Molecular and Cell Biology, Baylor College of Medicine
Languages: English
Get to know Chandrasekhar Yallampalli, DVM, PhD
Dr. Yallampalli is reproductive endocrinologist with an excellent research career in the areas of vascular adaptations during pregnancy and various pregnancy related disorders such as preeclampsia, gestational diabetes, fetal growth restriction. He has mentored numerous students, post-doctoral and clinical research fellows, and junior faculty members. Dr. Yallampalli’s research was funded primarily by the National Institutes of Health for over 30 years, and he has published over 200 peer reviewed scientific papers. He is a frequent presenter at conferences and meetings in his field. He serves on various committees reviewing grants for their merit at NIH. He is a member on several committees at Baylor College of Medicine.
Personal Statement
I have a broad background in endocrinology with specific training and expertise in reproductive endocrinology, vascular physiology, adaptations during pregnancy, sex-steroid hormone regulation of vascular adaptations, and feto-placental function.
In my current role, I use my expertise and leadership skills to successfully direct the research of the Women’s Reproductive Health Research scholars in this training grant. As PI or co-investigator on numerous university and NIH-funded grants over the last 30+ years, I have mentored junior researchers in writing successful grants and in career direction.
In my laboratory, trainees can choose projects involving both animal and human tissues while using a variety of molecular, biochemical, and systems biology approaches.
Some of my career highlights include relocating to the Baylor College of Medicine in September 2013 after a productive 26-years career at The University of Texas Medical Branch and my participation in the Annual Texas Forum for Reproductive Sciences, which I have organized for over 10 years and have been the primary coordinator for since 2015.
Clinical Interests
Preeclampsia, gestational diabetes
Education
| School | Education | Degree | Year |
|---|---|---|---|
| Medical Research Council of Canada University of Western Ontario, London, Ontario, Canada | Fellowship | Reproductive Biology | 1988 |
| University of Adelaide, Adelaide, Australia | PhD | Doctor of Philosophy in Reproductive Endocrinology | 1986 |
| Indian Veterinary Research Institute, Izatnagar, U.P., India | Masters | Master of Veterinary Sciences, (1st Rank in the institute) | 1977 |
| A.P. Agricultural University, Hyderabad, A.P., India | Bachelors | Bachelor of Veterinary Sciences (1st rank in the university) | 1975 |
Organizations
| Organization Name | Role |
|---|---|
| American Society for Advancement of Science | Member (1988-Present) |
| American Society of Reproductive Medicine | Member (1988-Present) |
| Association of Physiologist and Pharmacologist of India | Lifetime Member (since 1992) |
| Developmental Origins of Health and Disease (DoHaD) | Member (2003-Present) |
| Endocrine Society | Member (1987-Present) |
| Perinatal Research Society | Member (1995-present) Elected |
| Society for the Study of Reproduction | Member (1986-Present) Elected |
| Society of Gynecological Investigation | Member (1994-Present) |
Honors and awards
- 2012
-
Recipient, Distinguished Chair in Obstetrics and Gynecology, The University of Texas Medical Branch
- 2007
-
Mentor Recipient, President’s Presenter’s Award, Society for Reproductive Investigation
- 2004
-
Recipient, Distinguished Professorship for Mentoring and Research Excellence, The University of Texas Medical Branch
- 1996-2000
-
Mentor Recipient, President’s Presenter’s Award, Society for Reproductive Investigation
- 1975
-
Gold Medal (for first rank in BVSc), Andhra Pradesh Agricultural University
* Texas Children’s Hospital physicians’ licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician’s office and were not verified by Texas Children’s Hospital.
Research interests
Role of calcitonin gene-related peptide family in vascular adaptions during pregnancy and by sex steroids, placental functions, and fetal growth regulation
Role of sex steroids in regulating the mechanisms underlying thein utero protein-restricted diet-induced programming of progeny’s adult hypertension and diabetes
Role of complement in the pathology of preeclampsia
Involvement of adrenomedullin in the lipid metabolism and its role in gestational diabetes
Vidyadharan VA, Betancourt A, Smith, C, Blesson CS, Yallampalli C. Maternal Low-Protein Diet Leads to Mitochondrial Dysfunction and Impaired Energy Metabolism in the Skeletal Muscle of Male Rats. International Journal of Molecular Sciences, 2024 Nov 29;25(23):12860. doi: 10.3390/ijms252312860. PMID: 39684571.
Mishra A, Betancourt A, VidyadharanVA, Blesson CS, Belfort M, Yallampalli C, Chauhan M. Calcitonin gene-related peptide protects from soluble fms-like tyrosine kinase-1-induced vascular dysfunction in a preeclampsia mouse model. Front Physiology, 2023 Aug 31;14:1221684.PMID: 37719463.
Dong Y, BetancourtA, Belfort MA, Yallampalli C. Lipid dysfunction and adrenomedullin expression in omental versus subcutaneous adipose tissues in diabetic pregnancies. PLoS One, 2022 Apr 7;17(4):e0265419. PMID: 35390031
Dong Y, Ruano SH, Mishra A, Pennington KA, Yallampalli C. Adrenomedullin and its receptors are expressed in mouse pancreatic-cells and suppresses insulin synthesis and secretion. PLoS One, 2022 Mar 24;17(3):e0265890. PMID: 35324977.
Blesson CS, Schutt AK, Vipin VA, Tanchico DT, Mathew PR, Balakrishnan M, Bethancourt A, Yallampalli C. In Utero Low Protein Diet Programmed Type 2 Diabetes in adult offspring is mediated by Sex Hormones in Rats†. Biology of Reproduction, 2020 Oct 29;103(5):1110-1120. PMID: 32766739
Banadakoppa M, Pennington K, Balakrishnan M, Yallampalli, C. Complement inhibitor Crry expression in mouse placenta is essential for maintaining normal blood pressure and fetal growth. PLoS One, 2020 Aug 3;15(8):e0236968. PMID: 32745140.
Ghanda KB, Starosolski ZA, Bhayana S, Stupin I, Patel CV, Bhavane RC, Gao H, Bednov A, Yallampalli C, Belfort M, George V, Annapragada AV. Pre-clinical evaluation of a nanoparticle-based blood-pool contrast agent for MRI imaging of the placenta. Placenta, 2017 Sep; 57:60-70. PMID:28864020.