Huda Y. Zoghbi, MD

Director, Duncan Neurological Research Institute
Ralph D. Feigin, M.D., Endowed Chair
Distinguished Service Professor, Baylor College of Medicine
Investigator, Howard Hughes Medical Institute
Member, American Academy of Arts and Sciences, National Academy of Medicine and National Academy of Sciences

Education

School	Education	Degree	Year
Baylor College of Medicine	Fellowship	Research Fellowship	1988
Baylor College of Medicine	Residency	Neurology	1985
Baylor College of Medicine	Residency	Pediatrics	1982
Baylor College of Medicine	Internship	Pediatrics	1980
Meharry Medical College School of Medicine	Medical School	Doctor of Medicine	1979

About

Dr. Huda Y. Zoghbi is the Ralph D. Feigin Professor in the Departments of Pediatrics, Molecular and Human Genetics, Neurology, and Neuroscience, Baylor College of Medicine, and an Investigator for the Howard Hughes Medical Institute. Additionally, Dr. Zoghbi is the director of the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children's Hospital and Baylor College of Medicine (BCM), and was awarded the 2011 Neuroscience Prize of The Peter and Patricia Gruber Foundation for her pioneering work in unlocking the genetic and molecular mysteries behind a number of devastating neurological disorders, including Rett syndrome, spinocerebellar ataxia type 1, and brain tumors called medulloblastomas. Currently Dr. Zoghbi has four major research projects underway in the Zoghbi. For more information on those projects and the Zoghbi lab, go to the NRI website.

Organizations

Organization Name	Role
Alpha Omega Alpha Medical Honor Society	Member
American Academy of Neurology	Member
American Neurological Association	Member
American Society Human Genetics	Member
Child Neurology Society	Member

Selected Publications

Coffin SL, Durham MA, Nitschke L, Xhako E, Brown AM, Revelli J-P, Gonzalez EV, Lin T, Handler HP, Dai Y, Trostle AJ, Wan Y-W, Liu Z, Sillitoe RV, Orr HT, and Zoghbi HY. 2023. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron, in press.

Kim J, de Haro M, Al-Ramahi I, Garaicoechea L, Jeong H-H, Sonn J, Liu Z, Botas J, and Zoghbi HY. 2023. Evolutionarily conserved regulators of tau identify targets for new therapies. Neuron, in press

He L, Caudill MS, Jing J, Wang W, Sun Y, Tang J, Jiang X, Zoghbi HY. 2022. A weakened recurrent circuit in the hippocampus of Rett syndrome mice disrupts long-term memory representations. Neuron, May18;110(10):1689-1699. E6. PMID: 35290792.
This paper was the subject of a Neuron Editorial by Poll S and Fuhrmann M, May 18;110(10):1606-1608.

Achilly N, Wang W, Zoghbi HY. 2021. Presymptomatic training mitigates functional deficits in Rett syndrome mice. Nature.Apr;592(7855):596-600. PMCID: PMC8093094.

Shao, Y, Sztainberg Y, Wang Q, Bajikar SS, Trostle AJ, Wan Y-W, Jafar-Nejad P, Rigo F, Liu Z, Tang J, Zoghbi HY. 2021. Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome. Sci Transl Med. Mar 3;13(583):eaaz7785. PMID: 33658357.

View a complete list of publications by Huda Y. Zoghbi, M.D.

Awards & Honors

Award name	Date
August M. Watanabe Prize in Translational Research Indiana University School of Medicine	2023
Elaine Redding Brinster Prize in Science or Medicine Penn Institute for Regenerative Medicine at the University of Pennsylvania	09/2022
Kavli Prize in Neuroscience The Norwegian Academy of Science and Letters	06/2022
Brain Prize The Lundbeck Foundation	01/2020
Victor McKusick Leadership Award American Society of Human Genetics	09/2019
National Academy of Inventors	01/2019
Norman J. Siegel Award American Pediatric Society	01/2019
National Order of the Cedar, Lebanon Lebanon	01/2018
Member of American Association of Arts and Sciences	01/2018
Canada Gairdner International Award	01/2017
Breakthrough Prize in Life Sciences	01/2017
Shaw Prize in Life Science and Medicine	01/2016
Jesse Stevenson Kovalenko Medal	01/2016
Vanderbilt Prize in Biomedical Science	01/2015
Sckolnick Prize McGovern Institute for Brain Research at MIT	01/2014
March of Dimes Prize in Developmental Biology March of Dimes	01/2014
Honorary Doctorate of Science Yale University	01/2014
Dickson Prize in Medicine University of Pittsburg School of Medicine	01/2013
The Pearl Meister Greengard Prize The Rockefeller University	01/2013
Gruber Prize in Neuroscience	01/2011
Vilcek Prize for Biomedical Research	01/2009
International Rett Syndrome Foundation's Circle of Angels Research Award	01/2009
Marion Spencer Fay Award Drexel University College of Medicine Philadelphia, PA	01/2009
Texas Women's Hall of Fame Award Texas Governor's Commission for Women Abilene, TX	01/2008
Honorary Doctorate of Science Meharry Medical School Nashville, TN	01/2008
Honorary Doctorate of Science Middlebury College Middlebury, VT	01/2007
Robert J. and Claire Pasarow Foundation Award in Neuropsychiatry Los Angeles, CA	01/2007
Bristol-Myers Squibb Neuroscience Distinguished Achievement Award	01/2006
Elected National Academy of Sciences	01/2004
Marta Philipson Award in Pediatrics Philipson Foundation for Research Stockholm, Sweden	01/2004
Neuronal Plasticity Prize IPSEN Foundation Lisbon, Portugal	01/2004
Bernard Sachs Award Child Neurology Society	01/2001
Elected Institute of Medicine, National Academy of Sciences	01/2000
Javits Award NINDS Council, National Institutes of Health	01/1998
Soriano Award The American Neurological Association	01/1998
Sidney Carter Award American Academy of Neurology	01/1998
E. Mead Johnson Award Society of Pediatric Research	01/1996
Kilby Award for Extraordinary Contributions to Society	01/1995

Language

Arabic, English, French

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* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.

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