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Huda Zogbhi




Texas Medical Center

Phone: 713-798-6523
Fax: (713) 798-8728


One Baylor Plaza
Houston, TX 77030

Huda Y. Zoghbi, MD

Director, Duncan Neurological Research Institute
Ralph D. Feigin, M.D., Endowed Chair
Distinguished Service Professor, Baylor College of Medicine
Investigator, Howard Hughes Medical Institute
Member, American Academy of Arts and Sciences, National Academy of Medicine and National Academy of Sciences 


School Education Degree Year
Baylor College of Medicine Fellowship Research Fellowship 1988
Baylor College of Medicine Residency Neurology 1985
Baylor College of Medicine Residency Pediatrics 1982
Baylor College of Medicine Internship Pediatrics 1980
Meharry Medical College School of Medicine Medical School Doctor of Medicine 1979


Dr. Huda Y. Zoghbi is the Ralph D. Feigin Professor in the Departments of Pediatrics, Molecular and Human Genetics, Neurology, and Neuroscience, Baylor College of Medicine, and an Investigator for the Howard Hughes Medical Institute. Additionally, Dr. Zoghbi is the director of the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children's Hospital and Baylor College of Medicine (BCM), and was awarded the 2011 Neuroscience Prize of The Peter and Patricia Gruber Foundation for her pioneering work in unlocking the genetic and molecular mysteries behind a number of devastating neurological disorders, including Rett syndrome, spinocerebellar ataxia type 1, and brain tumors called medulloblastomas. Currently Dr. Zoghbi has four major research projects underway in the Zoghbi. For more information on those projects and the Zoghbi lab, go to the NRI website.


Organization Name Role
Alpha Omega Alpha Medical Honor Society Member
American Academy of Neurology Member
American Neurological Association Member
American Society Human Genetics Member
Child Neurology Society Member

Selected Publications

Coffin SL, Durham MA, Nitschke L, Xhako E, Brown AM, Revelli J-P, Gonzalez EV, Lin T, Handler HP, Dai Y, Trostle AJ, Wan Y-W, Liu Z, Sillitoe RV, Orr HT, and Zoghbi HY. 2023. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron, in press.

Kim J, de Haro M, Al-Ramahi I, Garaicoechea L, Jeong H-H, Sonn J, Liu Z, Botas J, and Zoghbi HY. 2023. Evolutionarily conserved regulators of tau identify targets for new therapies. Neuron, in press

He L, Caudill MS, Jing J, Wang W, Sun Y, Tang J, Jiang X, Zoghbi HY. 2022. A weakened recurrent circuit in the hippocampus of Rett syndrome mice disrupts long-term memory representations. Neuron, May18;110(10):1689-1699. E6. PMID: 35290792. 
This paper was the subject of a Neuron Editorial by Poll S and Fuhrmann M, May 18;110(10):1606-1608.

Achilly N, Wang W, Zoghbi HY. 2021. Presymptomatic training mitigates functional deficits in Rett syndrome mice. Nature.Apr;592(7855):596-600. PMCID: PMC8093094.

Shao, Y, Sztainberg Y, Wang Q, Bajikar SS, Trostle AJ, Wan Y-W, Jafar-Nejad P, Rigo F, Liu Z, Tang J, Zoghbi HY. 2021. Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome. Sci Transl Med. Mar 3;13(583):eaaz7785. PMID: 33658357.

View a complete list of publications by Huda Y. Zoghbi, M.D.

Awards & Honors

Award name Date
August M. Watanabe Prize in Translational Research
Indiana University School of Medicine
Elaine Redding Brinster Prize in Science or Medicine
Penn Institute for Regenerative Medicine at the University of Pennsylvania
Kavli Prize in Neuroscience
The Norwegian Academy of Science and Letters
Brain Prize
The Lundbeck Foundation
Victor McKusick Leadership Award
American Society of Human Genetics
National Academy of Inventors 01/2019
Norman J. Siegel Award
American Pediatric Society
National Order of the Cedar, Lebanon
Member of American Association of Arts and Sciences 01/2018
Canada Gairdner International Award 01/2017
Breakthrough Prize in Life Sciences 01/2017
Shaw Prize in Life Science and Medicine 01/2016
Jesse Stevenson Kovalenko Medal 01/2016
Vanderbilt Prize in Biomedical Science 01/2015
Sckolnick Prize
McGovern Institute for Brain Research at MIT
March of Dimes Prize in Developmental Biology
March of Dimes
Honorary Doctorate of Science
Yale University
Dickson Prize in Medicine
University of Pittsburg School of Medicine
The Pearl Meister Greengard Prize
The Rockefeller University
Gruber Prize in Neuroscience 01/2011
Vilcek Prize for Biomedical Research 01/2009
International Rett Syndrome Foundation's Circle of Angels Research Award 01/2009
Marion Spencer Fay Award
Drexel University College of Medicine
Philadelphia, PA
Texas Women's Hall of Fame Award
Texas Governor's Commission for Women
Abilene, TX
Honorary Doctorate of Science
Meharry Medical School
Nashville, TN
Honorary Doctorate of Science
Middlebury College
Middlebury, VT
Robert J. and Claire Pasarow Foundation Award in Neuropsychiatry
Los Angeles, CA
Bristol-Myers Squibb Neuroscience Distinguished Achievement Award 01/2006
National Academy of Sciences
Marta Philipson Award in Pediatrics
Philipson Foundation for Research
Stockholm, Sweden
Neuronal Plasticity Prize
IPSEN Foundation
Lisbon, Portugal
Bernard Sachs Award
Child Neurology Society
Institute of Medicine, National Academy of Sciences
Javits Award
NINDS Council, National Institutes of Health
Soriano Award
The American Neurological Association
Sidney Carter Award
American Academy of Neurology
E. Mead Johnson Award
Society of Pediatric Research
Kilby Award for Extraordinary Contributions to Society 01/1995


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* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.