Chester J. Koh, MD
Department or Service
- Texas Medical Center
Associate Professor of Urology (Pediatric), OB/GYN, and Pediatrics
Texas Children's Hospital
|Boston Children's Hospital - Urology||fellowship||Pediatric Urology||2005|
|University of Southern California||residency||Urology||2002|
|University of Southern California||internship||General Surgery||1997|
|Tufts University School of Medicine||medical school||Doctor of Medicine||1996|
About Chester J. Koh
My clinical area of expertise and interest is in minimally invasive surgery in children for their pediatric urologic conditions, especially with robotic surgery and single incision laparoscopic surgery, and I am the director of the Pediatric Robotic Surgery Program. We have shown that minimally invasive surgery in children has been associated with smaller incisions, shorter hospital stays, and decreased pain medication usage in comparison to open surgery in the field of pediatric urology for procedures such as pyeloplasty for ureteropelvic junction (UPJ) obstruction, nephrectomy (kidney removal), and ureteral reimplantation for vesicoureteral reflux. This often leads to faster recoveries for children, and allows their parents to minimize their time away from work. Robotic surgery can also be used for select genitourinary reconstructive procedures in pediatric urology as well. Our program serves as a pediatric robotic surgery research and training center that collaborates with the other institutions here in the Texas Medical Center.
I collaborate with our Pediatric Urology Laboratory, which is supported in part by NIH funding, as my NIH-funded laboratory in the past investigated novel therapeutic pathways for bladder regeneration / inflammation and other non-cancer urologic conditions.
I also serve as a principal investigator and founding co-director of a FDA-supported pediatric medical device consortium (the Southern California Center for Technology and Innovation in Pediatrics (CTIP)), a pediatric medical device consortium that is based in Los Angeles and which includes Texas Children's Hospital and Baylor College of Medicine (www.txctip.com). This 5 year grant (P50 FD004896 - Koh / Bar-Cohen) from the FDA's Office of Orphan Product Development is dedicated to improving children's health by supporting the development of innovative pediatric medical devices through all of the necessary stages - concept formation, prototyping, preclinical, clinical, manufacturing, marketing, and commercialization. The need for these consortia arose from the slow pace of pediatric medical device development, which currently lags behind the development of adult devices by five to ten years. In addition, children differ from adults in terms of their size, growth, development, body chemistry, and disease propensity.
|American Academy of Pediatrics, Section on Urology||Fellow|
|American College of Surgeons||Fellow|
|American Urological Association||AUA Leadership Program Graduate|
|Korean American Medical Association||Board Member|
|Society for Pediatric Urology||Executive Council Member|
Chung S, Kang DO, Yamzon J, Warburton D, and Koh CJ. Down-regulation of O-GlcNAc-mediated Glycosylation in Cyclophosphamide-induced Cystitis. Journal of Urology 183(1): 351-6, 2010. PMCID: PMC2840040, NIHMS .
Behan JW, Kim SS, Dorey FJ, De Filippo RE, Chang AY, Hardy BE, and Koh CJ. Human Capital Gains Associated with Robotic-Assisted Laparoscopic Pyeloplasty in Children Compared to Open Pyeloplasty. Journal of Urology 186(4 Suppl):1663-7, 2011. PMID: 21862079.
Kim PH, Patil M, Kim SS, Dorey FJ, De Filippo RE, Chang AY, Hardy BE, Gill IS, Desai MM, and Koh CJ. Early Comparison of Nephrectomy Options in Children (Open, Transperitoneal Laparoscopic, Laparo-Endoscopic Single Site (LESS), and Robotic Surgery). BJU Int 109(6):910-5, 2012. PMID: 21883858.
Silay MS, Baek M, Koh CJ. Robotic-assisted Laparoscopic Extravesical Ureteral Reimplantation in Children: Top-Down Suturing Technique Without Stent Placement. Journal of Endourology 2015 Aug;29(8):864-6. PMID: 25674670.
Afsarlar CE, Ryan SL, Donel E, Baccam TH, Jones B, Chandwani B, Au J, Huang GO, Gonzales ET, Janzen N, Tu D, Seth A, Roth DR, and Koh CJ. Standardized Process to Improve Patient Flow From the Emergency Room (ER) to the Operating Room (OR) for Pediatric Patients with Testicular Torsion. Journal of Pediatric Urology 2016 May 15. pii: S1477-5131(16)30046-8. doi: 10.1016/j.jpurol.2016.04.019. [Epub ahead of print]. PMID: 27270069.
Silay MS, Spinoit AF, Undre S, Fiala V, Tandogdu Z, Garmanova T, Guttilla A, Sancaktutar AA, Haid B, Waldert M, Goyal A, Serefoglu EC, Baldassarre E, Manzoni G, Radford A, Subramaniam R, Cherian A, Hoebeke P, Jacobs M, Rocco B, Yuriy R, Zattoni F, Kocvara R, and Koh CJ. Global Minimally Invasive Pyeloplasty Study in Children: Results from the Pediatric Urology Expert Group of the EAU Young Academic Urologists Working Party. Journal of Pediatric Urology 2016 May 12. pii: S1477-5131(16)30031-6. doi: 10.1016/j.jpurol.2016.04.007. [Epub ahead of print]. PMID: 27346071.
Choi IS, Yu KK, Kim J, Guzman E, Weisenberger DJ, Oghamian S, Kim HJ, Lee KH, Carroll C, Trinh BN, Kim M, Houshdaran S, Laird PW, Jones PA, Warburton D, Liang G, and Koh CJ. Alterations in the DNA Methylation Patterns of Calca, Timp3, Mmp2, and Igf2r Associated with Chronic Cystitis in a Cyclosphosphamide-induced Mouse Model. Urology. 2013 Jul;82(1):253.e9-15. doi: 10.1016/j.urology.2013.04.010. PMID: 23806407.