Binoy Shivanna, MD



Phone: 832-826-1830
Fax: 832-825-2799

Contact Information

6621 Fannin
WT 6-104
Houston, TX 77030
United States
Texas US

Attending Neonatologist
Associate Professor, Baylor College of Medicine

Texas Children's Hospital


School Education Degree Year
Baylor College of Medicine fellowship Neonatology 2010
Newark Beth Israel Medical Center residency Pediatrics 2007
Lokmanya Tilak Municipal Medical fellowship Neonatology 2002
University of Mysore Medical College residency Pediatrics 1997
University of Mysore Medical College medical school Bachelor of Medicine & Surgery 1993


We plan to understand the signaling pathways involved in the lung inflammatory processes, which contribute to the development of bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH). In particular, we are interested in investigating the role of adrenomedullin and regulatory T cells in hyperoxia- and lipopolysaccharide-induced injury in neonatal murine lungs and human neonatal lung derived cells, and translate our bench research to clinical trials for the prevention and or treatment of BPD-associated PH in premature infants.


Organization Name Role
American Academy of Pediatrics Fellow
American Academy of Pediatrics, Section on Perinatal Pediatrics Member
National Neonatology Forum of India Member
Southern Society for Pediatric Research Member
Texas Pediatric Society Member

Selected Publications

Shrestha AK, Bettini ML, Menon R, Gopal VYN, Huang S, Edwards DP, Pammi M, Barrios R, Shivanna B (2018). Consequences of Early Postnatal Lipopolysaccharide Exposure on Developing Lungs in Mice. Am J Physiol Lung Cell Mol Physiol. Jan 1; 316(1):L229-L244. PMID: 30307313.

Shivanna B, Gowda S, Welty SE, Barrington KJ, Pammi M (2019). Prostanoids and their analogues for the treatment of pulmonary hypertension in neonates. Cochrane Database Syst Rev Oct 1; 10:CD012963. PMID: 31573068.

Xiong T, Kulkarni M, Gokulakrishnan G, Shivanna B, Pammi M (2020). Natriuretic peptides in bronchopulmonary dysplasia: a systematic review. J Perinatol Apr;40(4):607-615. PMID: 31925319.

Menon RT, Shrestha AK, Reynolds CL, Barrios R, Caron KM, Shivanna B (2020). Adrenomedullin Is Necessary to Resolve Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension in Mice. Am J Pathol Mar;190(3):711-722. PMID: 32093901 (Manuscript selected for news release).

Menon RT, Shrestha AK, Barrios R, Reynolds CL, Shivanna B (2020). Tie-2 Cre-Mediated Deficiency of Extracellular Signal-Regulated Kinase 2 Potentiates Experimental Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension in Neonatal Mice. Int J Mol Sci Mar 31;21(7). pii: E2408. doi: 10.3390/ijms21072408. PMID: 32244398.

El-Saie A and Shivanna B (2020). Novel Strategies to Reduce Pulmonary Hypertension in Infants with Bronchopulmonary Dysplasia. Front. Pediatr 8:201. doi: 10.3389/fped.2020.00201. PMID: 32457857.

Shrestha AK, Menon RT, El-Saie AL, Barrios R, Reynolds CL, Shivanna B (2020). Interactive and Independent Effects of Early Lipopolysaccharide and Hyperoxia Exposure on Developing Murine Lungs. Am J Physiol Lung Cell Mol Physiol Sep 9. doi: 10.1152/ajplung.00013.2020. Online ahead of print.PMID: 32901520.