Binoy Shivanna, MD
Specialty
Phone: 832-826-1830
Contact Information
Attending Neonatologist
Associate Professor, Baylor College of Medicine
Texas Children's Hospital
Education
| School | Education | Degree | Year |
|---|---|---|---|
| Baylor College of Medicine | fellowship | Neonatology | 2010 |
| Newark Beth Israel Medical Center | residency | Pediatrics | 2007 |
| Lokmanya Tilak Municipal Medical | fellowship | Neonatology | 2002 |
| University of Mysore Medical College | residency | Pediatrics | 1997 |
| University of Mysore Medical College | medical school | Bachelor of Medicine & Surgery | 1993 |
About
We plan to understand the signaling pathways involved in the lung inflammatory processes, which contribute to the development of bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH). In particular, we are interested in investigating the role of adrenomedullin and regulatory T cells in hyperoxia- and lipopolysaccharide-induced injury in neonatal murine lungs and human neonatal lung derived cells, and translate our bench research to clinical trials for the prevention and or treatment of BPD-associated PH in premature infants.
Organization
| Organization Name | Role |
|---|---|
| American Academy of Pediatrics | Fellow |
| American Academy of Pediatrics, Section on Perinatal Pediatrics | Member |
| National Neonatology Forum of India | Member |
| Southern Society for Pediatric Research | Member |
| Texas Pediatric Society | Member |
Selected Publications
Shrestha AK, Bettini ML, Menon R, Gopal VYN, Huang S, Edwards DP, Pammi M, Barrios R, Shivanna B (2018). Consequences of Early Postnatal Lipopolysaccharide Exposure on Developing Lungs in Mice. Am J Physiol Lung Cell Mol Physiol. Jan 1; 316(1):L229-L244. PMID: 30307313.
Shivanna B, Gowda S, Welty SE, Barrington KJ, Pammi M (2019). Prostanoids and their analogues for the treatment of pulmonary hypertension in neonates. Cochrane Database Syst Rev Oct 1; 10:CD012963. PMID: 31573068.
Xiong T, Kulkarni M, Gokulakrishnan G, Shivanna B, Pammi M (2020). Natriuretic peptides in bronchopulmonary dysplasia: a systematic review. J Perinatol Apr;40(4):607-615. PMID: 31925319.
Menon RT, Shrestha AK, Reynolds CL, Barrios R, Caron KM, Shivanna B (2020). Adrenomedullin Is Necessary to Resolve Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension in Mice. Am J Pathol Mar;190(3):711-722. PMID: 32093901 (Manuscript selected for news release).
Menon RT, Shrestha AK, Barrios R, Reynolds CL, Shivanna B (2020). Tie-2 Cre-Mediated Deficiency of Extracellular Signal-Regulated Kinase 2 Potentiates Experimental Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension in Neonatal Mice. Int J Mol Sci Mar 31;21(7). pii: E2408. doi: 10.3390/ijms21072408. PMID: 32244398.
El-Saie A and Shivanna B (2020). Novel Strategies to Reduce Pulmonary Hypertension in Infants with Bronchopulmonary Dysplasia. Front. Pediatr 8:201. doi: 10.3389/fped.2020.00201. PMID: 32457857.
Shrestha AK, Menon RT, El-Saie AL, Barrios R, Reynolds CL, Shivanna B (2020). Interactive and Independent Effects of Early Lipopolysaccharide and Hyperoxia Exposure on Developing Murine Lungs. Am J Physiol Lung Cell Mol Physiol Sep 9. doi: 10.1152/ajplung.00013.2020. Online ahead of print.PMID: 32901520.