Texas Children's Cancer and Hematology Center
Clinical Trials and Novel Therapies
As a recognized leader in clinical and laboratory research, we offer clinical trials and novel therapies for a wide range of children’s cancer and blood disorders.
Most of our patients are involved in a clinical trial or study. With over 250 active therapeutic clinical trials, our >350 researchers and 47 laboratories are pioneering the translation of discoveries to the clinic. As part of larger teams, our experts collaborate with the pharmaceutical industry and participate in major pediatric cancer and blood disorder cooperative clinical trial groups, like the Children’s Oncology Group (COG). See below for our current and featured trials.
C7R-GD2.CAR T Cells for Patients with GD2-expressing Brain Tumors (GAIL-B)
In this study, a new gene will be added to the GD2 T cells that can cause the cells to live longer. T cells need substances called cytokines to survive. The gene C7R has been added that gives the cells a constant supply of cytokine and helps them to survive for a longer period of time.
Read MoreRelapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study
The purpose of this study is to create a biobank for patients diagnosed with Sonic Hedgehog Medulloblastoma at Baylor College of Medicine/Texas Children's Cancer Center.
Read MoreHER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children with Ependymoma (PBTC-059)
This is a Phase I study to evaluate the safety profile of a type of immune therapy called HER2 CAR T cells. In addition to looking for side effects, we will study how well this treatment works against a brain tumor called ependymoma that has come back after treatment (recurrent) or has not responded well to treatment (progressive) in children.
Read MoreFor a complete list of clinical trials offered at Texas Children's Hospital, visit clinicaltrials.gov
Top 10 in Cancer
Proud to be ranked one of the best children’s cancer centers in the country by U.S. News & World Report for nine consecutive years
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