The 5th Biennial William T. Shearer "Innovations in Primary Immunodeficiency and Clinical Immunology" Symposium

William T. Shearer, MD, PhD
August 28, 1937 - October 9, 2018

“In my lifetime, I have been privileged to participate in the molecular and genetic advances that have given children with immunodeficiency and their families a better life.  This could only have happened at Baylor College of Medicine and Texas Children’s Hospital”

- William T. Shearer, MD, PhD


Fri, February 12, 2021

8:30 AM – 1:00 PM CST

About the Conference

The goal of the symposium is to increase awareness among the medical community of the importance of early detection of PIDD in this time of COVID-19 and assist in accurate diagnosis as there are more than 300 identified PIDD genes to date. It has been reported in published clinical retrospective studies that delayed diagnosis of PIDD results in increased morbidity and mortality. Furthermore, it has also been shown that there is a significant delay in the diagnosis of PIDD among physicians in the at-large community in comparison to the expert community. With the large number of genes that can contribute to PIDDs and also how similar genes can cause different clinical presentations in patients, it’s important to continually update the community on how to properly identify and diagnose patients.

Through presentations and discussions among physicians, scientists, and nurses on the utilization of new diagnostics tools for the early detection of PIDD, the vast improvement in patient outcome through early detection, and understanding emerging immunological barriers to the successful treatment of PIDD, is critically imperative to ameliorate avoidable morbidity and mortality among patients with PIDD.

Download Program


Rebecca H. Buckley, MD
James Buren Sidbury Distinguished Professor of Pediatrics, Professor of Immunology in the Department of Immunology, Duke University

Severe Combined Immunodeficiency: Saving Lives Through Early Diagnosis


Peter J. Hotez, MD, PhD
Dean for the National School of Tropical Medicine, Co-Director,

Texas Children's Hospital Center for Vaccine Development, Endowed Chair in Tropical Pediatrics, Professor. Departments of Pediatrics and Molecular Virology and Microbiology
Preventing the Next Pandemic: Vaccine Diplomacy in a Time of Anti-science


Lisa Forbes Satter, MD
Medical Director, Center for Human Immunobiology & Texas Children’s Hospital Infusion Center

COVID-19 infection in primary immunodeficiency patients


Neil Romberg, MD
Jeffrey Modell Endowed Chair of Pediatric Immunology Research, Assistant Professor of Pediatrics, University of Pennsylvania Institute for Immunology

PU.1-Mutated Agammaglobulinemia


Natalia Chaimowitz, MD, PhD
Instructor, Pediatrics - Allergy & Immunology
Texas Children’s Hospital

A Monogenic Cause of Infantile-Onset Inflammatory Bowel Disease


Tiphanie Vogel, MD, PhD
Assistant Professor of Pediatrics, Rheumatology and Center for Human Immunobiology

Clinically Unsolvable Autoinflammatory Disorder Diagnosed by RNA- followed by Long Read-Sequencing

Continued Education

Continuing Medical Education Accreditation Statement

Texas Children’s Hospital is accredited by Texas Medical Association to provide continuing medical education for physicians.

Credit Designation

Texas Children’s Hospital designates this live activity for a maximum of 2.0 AMA PRA Category 1 CreditsTM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.



Contact information

For questions or more information, please email Christina Cowperthwait at, (832) 824-1456