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Texas Medical Center

Diabetes and Endocrinology
Phone: 832-822-3670
Fax: 832-825-9069


6701 Fannin Street
11th Floor
Houston, TX 77030

Rebecca S. Aguirre, MD, PhD

Instructor of Pediatrics, Division of Diabetes and Endocrinology, Baylor College of Medicine


School Education Degree Year
Indiana University School of Medicine Fellowship Pediatric Endocrinology 2021
Indiana University School of Medicine Fellowship Endocrinology, Diabetes Metabolism 2019
Indiana University School of Medicine Residency Internal Medicine/Pediatrics 2017
Indiana University School of Medicine Internship Internal Medicine/Pediatrics 2014
Baylor College of Medicine Medical School Doctor of Medicine 2013
Baylor College of Medicine PhD Doctor of Philosophy 2011
Muhlenberg College Bachelors Bachelor of Science; Bachelor of Arts 2001


Rebecca Schneider Aguirre's is committed to providing compassionate, individualized care and believes in creating an environment where she can guide her patients through the ins-and-outs of their situations, creating a genuine collaborative and trusting partnership. As a physician-scientist, she enjoys the exchange between medicine and science and seeks to implement those advancements. 

Clinical Interests

Type 1 and type 2 diabetes 
Monogenic/MODY diabetes 
Secondary and atypical diabetes 
Hyperinsulinism and hypoglycemia 
General endocrinology (growth, early and Late puberty, thyroid, adrenal and pituitary conditions) 
Transitioning from the pediatric to adult model of care 

Research Interests

Pathogenesis of type 1 and type 2 diabetes 
Prevention of type 1 diabetes 

Selected Publications

Aguirre RS, Kulkarni A, Becker MW, Lei X, Sarkar S, Ramanadham S, Phelps EA, Nakayasu ES, Sims EK, Mirmira RG. Extracellular vesicles in ß cell biology: Role of lipids in vesicle biogenesis, cargo, and intercellular signaling. Mol Metab. 2022 09; 63:101545. PMID: 35817393. 
Davidson RK, Weaver SA, Casey N, Kanojia S, Hogarth E, Schneider Aguirre R, Sims EK, Evans-Molina C, Spaeth JM. The Chd4 subunit of the NuRD complex regulates Pdx1-controlled genes involved in ß-cell function. J Mol Endocrinol. 2022 06 14; 69(2):329-341. PMID: 35521759.    
Schneider Aguirre R, Khalid A, Ismail HM, Nabhan Z. Methimazole Desensitization in a 4-Year-Old With Refractory Graves Disease. AACE Clin Case Rep. 2021 Jul-Aug; 7(4):273-276. PMID: 34307852. 
Schneider Aguirre R, Fuqua JS. Mental Health Disorders and Hyperthyroidism in the Pediatric Population. Pediatrics. 2019 11; 144(5). PMID: 31582536. 

Aguirre RS, Eugster EA. Central precocious puberty: From genetics to treatment. Best Practice & Research Clinical Endocrinology & Metabolism. 2018; 32(4): 343-354. PMID: 30086862. 

Chen ME, Aguirre RS, Hannon TS.  Methods for Measuring Risk for Type 2 Diabetes in Youth: The Oral Glucose Tolerance Test (OGTT). Current Diabetes Reports. 2018; 18(8):51. PMID: 29909550. 

Schneider Aguirre R, Karpen SJ.  Inflammatory Mediators Increase SUMOylation of Retinoid X Receptor a in a c-Jun N-Terminal Kinase-Dependent Manner in Human Hepatocellular Carcinoma Cells.  Molecular Pharmacology. 2013; 84(2): 218–226. PMID: 23690070. 

View VICCTR Publications

View PubMed Publications

* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.