Nancy Ghanayem, MD, MS


  • Texas Medical Center


Critical Care

Phone: 832-826-6230

Contact Information

6651 Main Street
MC E1420
Houston, TX 77030
United States

Director, Complex Cardiac Care

Texas Children's Hospital

Professor of Pediatrics, Section of Critical Care, Baylor College of Medicine


School Education Degree Year
Northwestern University masters Healthcare Quality & Patient Safety 2018
Medical College of Wisconsin fellowship Pediatric Critical Care 1999
Medical College of Wisconsin residency Pediatrics 1996
Rush Medical College medical school Doctor of Medicine 1993


Care of critical illness and medically complex disease is optimal when it is collaborative amongst the multiple specialists and disciplines, as well as inclusive of family/patient participation.  

Clinical Interests:

Intensive care medicine, perioperative cardiac care, complex medical care, univentricular heart disease, transitional care, health care quality

Research Interests:

Univentricular heart disease, perioperative care/monitoring, ventricular assist devices, outcomes, neurodevelopment


Organization Name Role
Advancing Cardiac Therapies Improving Outcomes Network (ACTION) Stakeholder
American Academy of Pediatrics (AAP) Fellow
American Heart Association (AHA) Member
National Pediatric Cardiology Quality Improvement Collaboration (NPCQIC) Stakeholder
Pediatric Cardiac Critical Care Consortium (PC4) Executive Board Member and Chair of Scientific Review Committee
Pediatric Cardiac Intensive Care Society (PCICS) Member (including Scientific Review Committee)
Society of Critical Care Medicine (SCCM) Member
Society of Thoracic Surgery (STS) Member

Selected Publications

Ghanayem NS, Hoffman GM, Mussatto KA, Cava JR, Frommelt PC, Rudd NA, Steltzer MM, Bevandic SM, Frisbee SJ, Jaquiss RDB, Litwin SB, Tweddell JS.  Home surveillance program prevents interstage mortality following the Norwood Procedure.  Journal of Thoracic and Cardiovascular Surgery  126(5):  1367-75, November 2003.

Ohye RG, Sleeper LA, Mahony L, Newburger JW, Pearson GD, Lu M, Goldberg CS, Tabbutt S, Frommelt PC, Ghanayem NS, Laussen PC, Rhodes JF, Lewis AB, Mital S, Ravishankar C, Williams IA, Dunbar-Masterson C, Atz AM, Colan S, Minich LL, Pizarro C, Kanter KR, Jaggers J, Jacobs JP, Krawczewski CD, Pike N, McCrindle BW, Virzi L, Gaynor JW; Pediatric Heart Network Investigators. Comparison of Shunt types in Norwood procedure for single-ventricle lesions. New England Journal of Medicine 2010 May 27;362(21):1980-92.  PMID: 20505177.

Ghanayem NS, Hoffman GM, Mussatto KA, Frommelt MA, Cava JR, Mitchell ME, Tweddell JS. Perioperative monitoring in high-risk infants after stage 1 palliation of univentricular congenital heart disease. Journal of Thoracic Cardiovascular Surgery July 2010.  PMID: 20621312.

Ghanayem NS, Allen KR, Tabbutt S, Atz AM, Clabby ML, Cooper DS, Eghtesady P, Frommelt PC, Gruber PJ, Hill KD, Kaltman JR, Laussen PC, Lewis AB, Lurito KJ, Minich LL, Ohye RG, Schonbeck JV, Schwartz SM, Singh RK, Goldberg CS, Pediatric Heart Network Investigators.  Interstage mortality after the Norwood procedure:  Results of the multicenter Single Ventricle Reconstruction trial.  Journal of Thoracic and Cardiovascular Surgery 2012 Oct;144(4):896-906. PMID: 22704284.

Hoffman GM, Brosig CL, Mussatto KM, Tweddell JS, Ghanayem NS.  Perioperative cerebral oxygen saturation in neonates with hypoplastic left heart syndrome and childhood neurodevelopmental outcome.  Journal of Thoracic and Cardiovascular Surgery 2013 Nov;146(5):1153-64. PMID: 23317941.

Rudd NA, Frommelt MA, Tweddell JS, Hehir DA, Mussatto KA, Frontier KD, Slicker JA, Bartz PJ, Ghanayem NS.  Improved interstage survival after the Norwood operation:  Outcomes from 10 years of home monitoring.  Journal of Thoracic and Cardiovascular Surgery 2014 Oct;148(4):1540-7. PMID: 24667026.

Tuomela, KE, Gordon JB, Cassidy LD, Johaningsmeir S, Ghanayem NS. Resource utilization associated with extracardiac co-morbid conditions following congenital heart surgery in infancy. Pediatric Cardiology 2017 2017 Jun;38(5):1065-1070.  PMID:  28456828.

Tweddell JS, Hoffman GM, Ghanayem NS, Frommelt MA, Mussatto KA, Berger S.  Hypoplastic Left Heart Syndrome. Moss and Adams’ Heart Diseases in Infants, Children and Adolescents – Including the Fetus and Young Adult, 7th and 8th editions.