Michelle L. Seymour, MD, PhD
Fellow
Languages: English
Departments:
Get to know Michelle L. Seymour, MD, PhD
Personal Statement
Dr. Seymour believes that identifying and reaching each child’s functional goals is a journey that requires the efforts of a multi-disciplinary team, and her priority is to guide and equip families in this process. As a dually-trained physician-scientist, she also seeks to enhance patient care through research that deepens understanding of functional outcomes and communication interventions.
Clinical Interests:
Her clinical interests include pediatric traumatic and acquired brain injury, cognitive communication impairments, augmented and alternative communication (AAC) devices, spasticity and dystonia management, electrodiagnostic medicine, and transition from pediatric to adult care for individuals with chronic diseases of childhood.
Research Interests:
In the research arena, Dr. Seymour is interested in receptive, expressive, and context-dependent language deficits in pediatric communication disorders; the impact of dystonia and movement disorders on AAC use; improving functional communication through AAC partner/facilitator training; and functional outcomes following pediatric traumatic and acquired brain injury.
Education
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* Texas Children’s Hospital physicians’ licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician’s office and were not verified by Texas Children’s Hospital.
Gober J, Seymour ML, Miao H, Curry DJ, Thomas SP. (2022) Management of severe spasticity with and without dystonia in the pediatric population: cross-sectional study of the use of intrathecal baclofen in a large pediatric tertiary hospital. World Journal of Pediatric Surgery 5:e000407. doi: 10.1136/wjps-2021-000407
Karri J, Seymour ML, Verduzco-Gutierrez M, Jayaram P. (2020) Point-of-care procedures in physiatry: practice considerations during the Covid-19 pandemic. American Journal of Physical Medicine & Rehabilitation 99(7): 567-570. PMID: 32398402
Chen CA, Wang W, Pedersen SE, Raman A, Seymour ML, Ruiz FR, Xia A, van der Heijgen ME, Wang L, Yin J, Lopez J, Rech ME, Lewis RA, Wu SM, Liu Z, Pereira FA, Pautler RG, Zoghbi HY and Schaaf CP. (2020) Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity. Hum Mol Genetic 29;5:705-715. PMID: 31600777
Lotfi P, Tse DY, Seymour ML, Cooper J, Pereira FA, Wu SM, and Sardiello M. (2018) Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency. Autophagy. 14;8:1419-1434. PMID: 29916295
Xie W, Jen HI, Seymour ML, Yeh SY, Pereira FA, Groves AK, Klisch TJ, Zoghbi HY. (2017) An Atoh1-S193A phosphor-mutant allele causes hearing deficits and motor impairment. Journal of Neuroscience. Sep 6;37(36):8583-8594. PMID: 28729444
Seymour ML, Rajagopalan L, Duret G, Volk MJ, Liu H, Brownell WE, Pereira FA. (2016) Membrane prestin expression correlates with the magnitude of prestin-associated charge movement. Hear Res. 339:50-9. PMID: 27262187
Seymour ML and Pereira FA. (2015) Survival of auditory hair cells. Cell Tissue Res. 361(1):59-63. PMID: 25743696