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Location

Texas Medical Center

Specialty
Cancer and Hematology
Phone: 713-798-5643
Email

Erin.Peckham-Gregory@bcm.edu

Address

1102 Bates Ave., Ste. 1570
Houston, TX 77030

Erin C. Peckham-Gregory, PhD, MPH

Assistant Professor, Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine

Education

School Education Degree Year
Baylor College of Medicine Post-doctoral Fellow NCI-funded R25T fellowship program in Pediatric Cancer Epidemiology and Control 2017
Fielding School of Public Health, University of California at Los Angeles PhD Doctor of Philosophy, Cancer Epidemiology 2014
University of California at Los Angeles Masters Master of Public Health 2014
University of California at Los Angeles Bachelors Bachelor of Science, Ecology and Evolutionary Biology 2007

Organizations

Organization Name Role
American Association for Cancer Research (AACR) Member
American Society of Hematology (ASH) Member
American Society of Preventive Oncology Member
Children’s Oncology Group (COG) Member
Histiocyte Society Member
International Lymphoma Epidemiology Consortium (InterLymph) Member

Research Statement

Erin Peckham-Gregory's primary research focus is to elucidate inherited genetic factors underlying susceptibility to pediatric lymphoproliferative and hematologic malignancies, with particular emphasis on Langerhans Cell Histiocytosis (LCH).

She is interested in how inherited genetic and epigenetic factors contribute to the development of pediatric lymphoproliferative malignancies, and am dedicated to a research career focused on the molecular epidemiology of these disorders.

As a National Cancer Institute-funded postdoctoral fellow in The Histiocytosis Program and the Epidemiology and Population Sciences Program at the Texas Children’s Cancer and Hematology Center and Baylor College of Medicine (BCM), she gained hands-on experience through collaboration with experts in the field to assess epidemiologic and genetic risk predictors of LCH.

She continues to broaden her research skill-set by participating in several statistical genetics workshops and numerous scientific conferences, in addition to gaining membership to relevant societies, including: the Histiocyte Society, North American Consortium for Histiocytosis, Children’s Oncology Group, International Lymphoma Epidemiology Consortium and the American Society of Hematology. Together, these experiences have prepared her to successfully research both the demographic and molecular determinants of lymphoproliferative diseases.

She has also worked extensively on the design of case-parent trio studies and associated analytics. Moreover, she utilized her training in epidemiologic methods, bioinformatics, genomics and epigenomics to develop an integrated approach for understanding the molecular underpinnings of LCH. Specifically, she conducted the first genome-wide association study (GWAS) of LCH and identified disease susceptibility loci that are associated with LCH risk and are enriched in specific racial/ethnic groups. Observations from this study may thus explain differences in susceptibility between different ethnic groups in a disease thought to be driven by somatic mutations.

Her current research objective is to characterize the role of inherited genetic effects on LCH susceptibility and identify germline genomic regions associated with LCH somatic mutations such as BRAF-V600E. Not only will this research uncover important aspects of susceptibility to LCH, it may inform fundamental mechanisms of cancer predisposition that contribute to ethnic disparities in incidence and outcomes of children and adults with tumors driven by BRAF-V600E.

Selected Publications

Awards & Honors

2016    Fellow Scholar Award in Clinical Research, American Society of Hematology (ASH)
2016    Thrasher Research Fund Early Career Award Program
2015    Selected Participant, American Association of Cancer Research Integrative Molecular Epidemiology Workshop
2013    Graduate Division Dissertation Year Fellowship, University of California at Los Angeles
2009    University Fellowship, University of California at Los Angeles
2009    NCI/NIH T32 Training Grant in Cancer Epidemiology, Cancer Epidemiology 
2007    California Wellness Foundation Fellowship, University of California at Los Angeles
2006    University National Science and Mathematics Access to Retain Talent (SMART) Grant, University National Science
 

Language

English



* Texas Children's Hospital physicians' licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician's office and were not verified by Texas Children's Hospital.