Eileen D. Brewer, MD
Dr. Brewer is an internationally known expert in pediatric renal diseases, dialysis, transplantation and hypertension. She is past president of the American Society of Pediatric Nephrology, former Council Member of the International Pediatric Nephrology Association and organizer of International Workshops on Hypertension in Children and Adolescents in 2001, 2004 and 2007. She has been an active clinician and clinical researcher throughout her career. She has participated as institutional Principal Investigator in numerous national multi-center clinical investigations such as the NIH-sponsored randomized, double-blind, placebo-controlled trial of antimicrobial prophylaxis in children with vesicoureteral reflux and urinary tract infection (RIVUR). Recent local studies have been conducted in collaboration with Dr. Poyyapakam Srivaths and Fellows in the Pediatric Renal Section, focusing on clinical investigation of fibroblastic growth factor 23, Klotho, vitamin D and dysfunctional mineral metabolism as potential cardiovascular risk factors in pediatric patients with end stage renal disease, including children with renal transplants or those maintained on chronic dialysis. Other collaborative renal transplant studies include evaluation of pediatric waitlist access to transplantation, of long-term outcomes of pediatric transplants and of ways to improve medical adherence for pediatric patients transitioning to adult transplant care. Dr. Brewer is author of over 90 journal articles and 30 book chapters and is frequently invited to speak at scientific meetings and workshops nationally and internationally.
Dr. Brewer strongly supports the importance of mentorship to help fellows and junior faculty find the right career path, become independent investigators and succeed as medical school faculty ready to teach the next generation. She currently mentors several faculty and fellows in the Renal Section. She also has experience in helping young pediatric nephrologists in developing countries. She collaborated from 2011-2013 as established center director to help an emerging center director, Dr. Randall Lou-Meda at Fundanier, Hospital Roosevelt in Guatemala City, develop his center’s fledgling pediatric renal fellowship training program and chronic kidney disease/dialysis/transplantation programs through a grant from the International Society of Nephrology Sister Renal Center Program. Dr. Brewer also mentors Dr. Peace Imani, Pediatric Renal Fellow at Baylor and recipient of a Thrasher Research Fund Early Career Award Program Grant (2015-2017) to study the impact of chronic kidney disease on health related quality of life of children in Uganda.
• End stage renal disease / chronic dialysis
• Kidney Transplantation
• Lowe Syndrome
• Tuberous sclerosis
• fibroblastic growth factor 23, Klotho, vitamin D and dysfunctional mineral metabolism in end stage renal disease
• Long-term outcomes of pediatric kidney transplant
• Impact of chronic kidney disease on health related quality of life of children in Uganda
Smith JM, Brewer ED. Decreasing living donor rates in pediatric kidney transplantation: A time for action. Pediatric Transplantation 21(2). PubMed PMID: 28191751, 2017.
Rana A, Brewer ED, Scully BB, Kueht ML, Goss M, Halazun KJ, Liu H, Galvan NT, Cotton RT, O'Mahony CA. Poor outcomes for children on the wait list at low-volume kidney transplant centers in the United States. Pediatric Nephrology PubMed PMID: 27757587, 2016.
Brewer ED, Swartz SM. Evaluation of Hypertension in Childhood Diseases. In Pediatric Nephrology, eds Avner ED, Harmon WE, Niaudet P, Yoshikawa N, Emma F, Goldstein SL, Springer Verlag, Heidelberg, 7th edition, Chap 81, pp 1997-2022, ISBN 978-3-662-43595-3, 2016.
Austin J, Bartosh SM, Bell L, Bellah R, Bhatnagar S, Brewer ED, Chesney RW, Mattoo TK, et al. (The RIVUR Trial Investigators). Antimicrobial prophylaxis for children with vesicoureteral reflux. New England Journal of Medicine 19; 370(25):2367-76, PubMed: PMC4137319, 2014.
Srivaths PR, Goldstein SL, Silverstein DM, Krishnamurthy R, Brewer ED. Elevated FGF 23 and phosphorus are associated with coronary calcification in hemodialysis patients. Pediatric Nephrology 26:945-51, PubMed PMID: 21359960, 2011.
ViiCTR Profile: https://profiles.viictr.org/display/BCM/eileen-brewer
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