Charles D. Fraser, Jr., MD

Department or Service


  • Texas Medical Center


Congenital Heart Surgery

Phone: 832-826-1929
Fax: 832-825-1904

Contact Information

6621 Fannin
MC WT 19345-H
Houston, TX 77030

Congenital Heart Surgeon

Texas Children's Hospital


School Education Degree Year
Johns Hopkins University School of Medicine residency Cardiovascular Surgery 1993
Royal Children's Hospital fellowship Pedi Cardiovascular Surgery 1992
Johns Hopkins University School of Medicine residency General Surgery 1990
Johns Hopkins University School of Medicine internship General Surgery 1985
University of Texas Medical Branch medical school Doctor of Medicine 1984

About Charles D. Fraser, Jr.

As senior surgeon in the Texas Children's Heart Center, Dr. Fraser and team work to refine the surgical treatment of small babies, children and adults with congenital cardiac disease. Dr. Fraser's focus is on the surgical care of these patients with particular emphasis on complex neonatal repairs and difficult reoperative cardiac surgery, valve repair, and adults with congenital heart disease. Dr. Fraser has developed dedicated pediatric heart and lung transplant and mechanical circulatory support teams to offer every available therapy in the care of critically ill children.

In addition to his role in Congenital Heart Surgery, Dr. Fraser served as Surgeon-in-Chief from 2001-2018 where he oversaw the entirety of the surgical enterprise including over 100 full time surgeons. Dr. Fraser developed focused programs to offer children in need of surgery the very best opportunity for a quality outcome, to promote cutting-edge research, and to educate tomorrow's leaders in children's subspecialty surgery. The surgical service with the TCH enterprise includes 31 operating rooms. In 2017 surgical services at Texas Children's Hospital performed almost 30,000 operations.

Dr. Fraser maintains an active research program with specific interests in congenital heart surgical outcomes and quality, transplantation, mechanical circulatory support, brain protection, and bioengineering. One of Dr. Fraser’s most passionate interests is in outcomes analysis and data/performance transparency. In 2002, his team developed the first pediatric lung transplant program in the Southwest, which has subsequently grown to be the nation's largest. In 2005, he performed the first successful pediatric heart/lung transplant in the Southwest. He implanted the world's first DeBakey Child Cardiac assist device in March of 2004. Dr. Fraser served as the National Principal Investigator of a pivotal, first ever, multi-center pediatric ventricular assist device trial to assess the safety and benefit of the Berlin Heart Pediatric EXCOR ventricular assist device. This device was subsequently approved in December 2011 by the U.S. Food and Drug Administration for clinical use - the first device to be approved specifically for small babies. In 2011, Dr. Fraser's heart failure team implanted the first total artificial heart at a children's hospital.

In collaboration with Rice University's Department of Bioengineering, Dr. Fraser continues to focus attention on bioengineering solutions to congenital heart defects. Dr. Fraser is also actively engaged in the study of neurologic outcomes following pediatric cardiac surgery.

Selected Publications

Adachi I, Jeewa A, Burki S, McKenzie ED, Fraser CD Jr.  Outpatient management of a child with bidirectional Glenn shunts supported with implantable continuous-flow ventricular assist device.  Journal of Heart and Lung Transplantation 2016 Feb 9.

Mery CM, Guzman-Pruneda FA, De Leon LE, Zhang W, Terwelp MD, Bocchini CE, Adachi I, Heinle JS, McKenzie ED, Fraser CD Jr.  Risk factors for development of endocarditis and reintervention in patients undergoing right ventricle to pulmonary artery valved conduit placement.  Journal of Thoracic Cardiovascular Surgery  2016 Feb;151(2):432-441.e2.

Fraser CD Jr.  Evolution of the Pediatric and Congenital Heart Surgery Service at Texas Children's Hospital:  1954-2015  Seminars in Thoracic Cardiovascular Surgery 2015 Winter;27(4):380-7.

Cabrera AG, Chen DW, Pignatelli RH, Khan MS, Jeewa A, Mery CM, McKenzie ED, Fraser CD Jr. Outcomes of anomalous left coronary artery from pulmonary artery repair:  beyond normal function.  Annals of Thoracic Surgery 2015 Apr;99(4):1342-7.

Adachi I, Khan MS, Guzman-Pruneda FA, Fraser CD 3rd, Mery CM, Denfield SW, Dreyer WJ, Morales DL, McKenzie ED, Heinle JHS, Fraser CD Jr.  Evolution and impact of ventricular assist device program on children awaiting heart transplantation.  Annals of Thoracic Surgery 2015 Feb;99(2):635-40.

Mery CM, Guzman-Pruneda FA, Carberry KE, Watrin CH, McChesney GR, Chan JG, Adachi I, Heinle JS, McKenzie ED, Fraser CD Jr.  Aortic arch advancement for aortic coarctation and hypoplastic aortic arch in neonates and infants.  Annals of Thoracic Surgery 2014 August;98(2):625-33.

Guzman-Pruneda FA, Fraser CD Jr.  Neuroprotective strategies---what do we really need to know?  Seminars in Thoracic Cardiovascular Surgery Pediatric Cardiac Surgery Annual 2014;17(1):77-80.

McKenzie ED, Khan MS, Dietzman TW, Guzman-Pruneda FA, Samayoa AX, Liou A, Heinle JS, Fraser CD Jr.  Surgical pulmonary valve replacement:  a benchmark for outcomes comparisons.  Journal of Thoracic Cardiovascular Surgery 2014 Oct;148(4):1450-3.

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